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Effects and mechanisms of Sirtuins family against atherosclerosis

Xi'an jiao tong da xue xue bao. Journal of Xi'an Jiaotong University (medical sciences). Yi xue ban, 2020-01 (3), p.309

Copyright Xi'an Jiaotong University 2020 ;ISSN: 1671-8259 ;DOI: 10.7652/jdyxb202003001

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  • Title:
    Effects and mechanisms of Sirtuins family against atherosclerosis
  • Author: LIN, Rong ; ZHENG Zihan
  • Subjects: Antioxidants ; Atherosclerosis ; Cardiovascular disease ; Fatty acids ; Fibroblasts ; Inflammation ; Kinases ; Metabolism ; Oxidative stress ; Proteins ; Senescence ; Smooth muscle
  • Is Part Of: Xi'an jiao tong da xue xue bao. Journal of Xi'an Jiaotong University (medical sciences). Yi xue ban, 2020-01 (3), p.309
  • Description: Sirtuins family is a class Ⅲ histone deacetylase of a highly conserved catalytic domain. Sirtuins family exerts effects on cancers, cardiovascular diseases, metabolic diseases and neurological diseases. Recent studies have found that Sirtuins members are closely related to the pathogenesis of atherosclerosis (As) by regulating the occurrence and development of As through diverse physiological mechanisms such as oxidative stress, energy metabolism and inflammatory response. We hope it provides evidence and direction for using SIRT1-SIRT7 as the target of As treatment.
  • Publisher: Xi'an: Xi'an Jiaotong University
  • Language: Chinese
  • Identifier: ISSN: 1671-8259
    DOI: 10.7652/jdyxb202003001
  • Source: ProQuest Central
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