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Combined application of optical methods to increase the information content of optical coherent tomography in diagnostics of neoplastic processes

Quantum electronics (Woodbury, N.Y.), 2002-11, Vol.32 (11), p.993-998 [Peer Reviewed Journal]

2003 INIST-CNRS ;ISSN: 1063-7818 ;EISSN: 1468-4799 ;DOI: 10.1070/QE2002v032n11ABEH002334

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Title:
Combined application of optical methods to increase the information content of optical coherent tomography in diagnostics of neoplastic processes
Author: Kuranov, R V ; Sapozhnikova, V V ; Shakhova, N M ; Gelikonov, V M ; Zagainova, E V ; Petrova, S A
Subjects: AMINO ACIDS ; AMINOLEVULINIC ACID ; BODY ; CARBOXYLIC ACIDS ; CARCINOMAS ; DIAGNOSTIC TECHNIQUES ; DIGESTIVE SYSTEM ; DISEASES ; EMISSION SPECTROSCOPY ; ESOPHAGUS ; FLUORESCENCE SPECTROSCOPY ; NEOPLASMS ; OPTICAL SYSTEMS ; ORGANIC ACIDS ; ORGANIC COMPOUNDS ; ORGANS ; PATHOLOGY ; POLARIZATION ; RADIOLOGY AND NUCLEAR MEDICINE ; SPECTROSCOPY ; TOMOGRAPHY
Is Part Of: Quantum electronics (Woodbury, N.Y.), 2002-11, Vol.32 (11), p.993-998
Description: A combined application of optical methods [optical coherent tomography (OCT), cross-polarisation optical coherent tomography, and fluorescence spectroscopy] is proposed for obtaining information on morphological and biochemical changes occurring in tissues in norm and pathology. It is shown that neoplastic and scar changes in esophagus can be distinguished using a combination of polarisation and standard OCT due to the difference between the depolarising properties of the tissues caused by the structural properties of collagenic fibres in stroma. It is shown that OCT combined with fluorescence spectroscopy with the use of 5-aminolevulinic acid is promising for determining the boundaries of carcinoma of the uterine cervix and vulva. It is found that the tumour boundary detected by optical methods coincides with the morphological boundary and extends beyond colposcopically determined boundary by about 2 mm. (laser biology and medicine)
Publisher: Woodbury, NY: IOP Publishing
Language: English;Russian
Identifier: ISSN: 1063-7818
EISSN: 1468-4799
DOI: 10.1070/QE2002v032n11ABEH002334
Source: Alma/SFX Local Collection

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Combined application of optical methods to increase the information content of optical coherent tomography in diagnostics of neoplastic processes

2003 INIST-CNRS ;ISSN: 1063-7818 ;EISSN: 1468-4799 ;DOI: 10.1070/QE2002v032n11ABEH002334

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