skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Search type Index

Treat-to-target (T2T) of serum urate (SUA) in gout: a clinical audit in real-world gout patients

Reumatismo, 2019-10, Vol.71 (3), p.154-159 [Peer Reviewed Journal]

2019. This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 0048-7449 ;EISSN: 2240-2683 ;DOI: 10.4081/reumatismo.2019.1225 ;PMID: 31649384

Full text available

Citations Cited by
  • Title:
    Treat-to-target (T2T) of serum urate (SUA) in gout: a clinical audit in real-world gout patients
  • Author: Teh, C L ; Cheong, Y K ; Wan, S A ; Ling, G R
  • Subjects: Adult ; Aged ; Female ; gout ; Gout - blood ; Gout - therapy ; Humans ; Male ; Medical Audit ; Middle Aged ; Practice Guidelines as Topic ; Retrospective Studies ; Treat to target (T2T) ; Uric Acid - blood
  • Is Part Of: Reumatismo, 2019-10, Vol.71 (3), p.154-159
  • Description: Treat-to-target (T2T) for gout has been established recently to improve its management, which has been reported to be sub-optimal with significant gaps between the goals of treatment and day-to-day clinical practice. T2T recommended a goal of serum urate (SUA) target of <360 μmoI/L in all patients with gout and <300 μmoI/L in patients with tophaceous or severe gout. T2T strategy was applied in the management of gout patients in two Rheumatology clinics from 1 January 2016 onwards. We performed a clinical audit to assess T2T of SUA in gout patients and to identify causes for failure to achieve target SUA among them. There were a total of 304 patients for our analysis. They were of multi-ethnic origin with male predominance (88.8%). They had a mean age of 57.7+13.7 years and mean disease duration of 10.1+8.7 years. The most common comorbidities were hypertension (76.2%), dyslipidemia (52.5%) and diabetes mellitus (DM) (27.4%). Our patients' body mass indexes showed that 47.7% were obese while 34.2% were overweight. Up to 62.4% of our patients had tophi and 42.6% had joint deformities. Only 34.9% of patients achieved target SUA. Nonadherence (52.3%) was the main reason identified for failure to achieve target SUA. The independent predictors for failure to achieve target SUA were nonadherence (HR=7.84, p=0.000) and presence of tophi (HR=1.95, p=0.001).
  • Publisher: Italy: PAGEPress Publications
  • Language: English;Italian
  • Identifier: ISSN: 0048-7449
    EISSN: 2240-2683
    DOI: 10.4081/reumatismo.2019.1225
    PMID: 31649384
  • Source: MEDLINE
    ProQuest Central
    DOAJ Directory of Open Access Journals
Back to results list
INSPIRE LIBRARY - TON DUC THANG UNIVERSITY (84-028) 37 755 057 Feedback
19 Nguyen Huu Tho St. Dist.7, HCM thuvien@tdtu.edu.vn

Copyright © 2017 INSPIRE LIBRARY - TON DUC THANG UNIVERSITY

Searching Remote Databases, Please Wait