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PREPARATION METHOD FOR DECELLULARIZED EXTRACELLULAR MATRIX TISSUE PAPER AND USE
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Title:
PREPARATION METHOD FOR DECELLULARIZED EXTRACELLULAR MATRIX TISSUE PAPER AND USE
Author:
ZHANG, Zhen
;
LI, Wen
;
ZHU, Meifeng
;
KONG, Deling
Subjects:
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
;
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
;
HUMAN NECESSITIES
;
HYGIENE
;
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
;
MEDICAL OR VETERINARY SCIENCE
;
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
Description:
Disclosed are a preparation method for decellularized extracellular matrix tissue paper and use, which belong to the technical field of regenerative medicine. The preparation method comprises the following steps: (1) preparing a decellularized extracellular matrix material; (2) preparing tissue paper: homogenizing the prepared decellularized extracellular matrix material, then placing the homogenate on a flat-bottom filter screen to remove water, letting the filtered homogenate to stand and be air-dried, and performing lyophilization to obtain the tissue paper; (3) cross-linking the tissue paper: placing the tissue paper in a cross-linking solution for cross-linking; and (4) lyophilizing or laminating the cross-linked tissue paper. The present invention uses a traditional papermaking technology in combination with a lyophilization technology to prepare tissue-specific decellularized extracellular matrix tissue paper. The process does not involve the use of acid, enzymes or organic solvents and thus is mild, a
Creation Date:
2023
Language:
Chinese;English;French
Source:
esp@cenet
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