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Thyroid function assessment in Saudi males with metabolic syndrome

Journal of pharmacy & bioallied science, 2021-10, Vol.13 (4), p.352-359 [Peer Reviewed Journal]

Copyright: © 2022 Journal of Pharmacy And Bioallied Sciences. ;COPYRIGHT 2021 Medknow Publications and Media Pvt. Ltd. ;2021. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Copyright: © 2022 Journal of Pharmacy And Bioallied Sciences 2022 ;ISSN: 0975-7406 ;ISSN: 0976-4879 ;EISSN: 0975-7406 ;DOI: 10.4103/jpbs.jpbs_745_21 ;PMID: 35399801

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Title:
Thyroid function assessment in Saudi males with metabolic syndrome
Author: Aldhafiri, Fahad ; Abdelgawad, Fathy ; Bakri, Gihan ; Saber, Tamer
Subjects: Biochemical markers ; Blood pressure ; Body mass index ; Cardiovascular diseases ; Cholesterol ; Dextrose ; Energy balance ; Fasting ; Glucose ; Glucose metabolism ; High density lipoprotein ; Homeostasis ; Hypothyroidism ; Insulin ; Lipid metabolism ; Lipids ; Low density lipoprotein ; Males ; Metabolic syndrome ; metabolic syndrome; thyroid and thyroid dysfunction; ldl/hdl cholesterol; obesity; hypertension; cardiovascular disease; lipids (tg) ; Physiological aspects ; Risk factors ; Statistical analysis ; Thyroid ; Thyroid gland ; Thyroid hormones ; Thyroid-stimulating hormone ; Thyroxine ; Triiodothyronine ; Type 2 diabetes
Is Part Of: Journal of pharmacy & bioallied science, 2021-10, Vol.13 (4), p.352-359
Description: Background: Metabolic Syndrome (MetS) is a multifactor condition associated with cardiovascular risk. Thyroid hormones regulate MetS components via controlling energy homeostasis, lipids, and glucose metabolism. The risk ratio for MetS and related disorders changes between males and females. Aim and Objectives: Study aim to access thyroid functions in Saudi population with metabolic syndrome. Materials and Methods: The current study sought to evaluate the impact of thyroid stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4) in predicting the risk of MetS. A total of 200 (MetS 100 and control 100) Saudi Arabian males were enrolled for the study, and after applying eligibility criteria, the eligible study size was examined for the physical test (chest, abdominal, and general examination with stress on blood pressure measurement) and anthropometric parameters (bodyweight, body mass index, and waist circumference). Results: In the present study, the biochemical parameters, such as TSH, FT3, FT4, total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), high-density lipoprotein (LDL), fasting glucose, and fasting insulin were measured in the study group, and statistical analysis was also performed. The results revealed that the MetS and control differ in terms of physical, anthropometric, and biochemical markers. The study showed that thyroid dysfunction (TD) and MetS are closely associated with the difference in physical, anthropometric, and metabolic characteristics. Conclusion: The result demonstrated hypothyroidism major risk factor due to TD in MetS. These findings provide a scientific basis for diagnosis and the management of TD, associated MetS, and cardiovascular disease (CVD).
Publisher: India: Wolters Kluwer India Pvt. Ltd
Language: English
Identifier: ISSN: 0975-7406
ISSN: 0976-4879
EISSN: 0975-7406
DOI: 10.4103/jpbs.jpbs_745_21
PMID: 35399801
Source: Geneva Foundation Free Medical Journals
Open Access: PubMed Central
AUTh Library subscriptions: ProQuest Central
ROAD: Directory of Open Access Scholarly Resources
DOAJ Directory of Open Access Journals

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Thyroid function assessment in Saudi males with metabolic syndrome

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