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Whipple's Disease Manifested as Recurrent Ascites

Curēus (Palo Alto, CA), 2017-03, Vol.9 (3), p.e1108 [Peer Reviewed Journal]

Copyright © 2017, Aamar et al. This work is licensed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Copyright © 2017, Aamar et al. 2017 Aamar et al. ;ISSN: 2168-8184 ;EISSN: 2168-8184 ;DOI: 10.7759/cureus.1108 ;PMID: 28439483

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  • Title:
    Whipple's Disease Manifested as Recurrent Ascites
  • Author: Aamar, Ali ; Madhani, Kamraan ; Anwar, Muhammad S ; Singh, Prabhdeep ; Garsten, Joel
  • Subjects: Gastroenterology ; Infectious Disease ; Internal Medicine
  • Is Part Of: Curēus (Palo Alto, CA), 2017-03, Vol.9 (3), p.e1108
  • Description: Whipple's disease commonly presents as chronic diarrhea and abdominal pain. Ascites is an uncommon presentation of Whipple's disease. Here, we report a rare case of a 47-year-old male who presented with diarrhea and abdominal distention for three months. The physical examination was significant for ascites. Serum albumin was low and serum-to-ascites albumin gradient was < 1.1 g/dl. This suggested that ascites was less likely to be present due to portal hypertension. Enteroscopy showed erythematous duodenum and jejunum; biopsy was suggestive of periodic acid-Schiff stain (PAS) positive macrophages consistent with Whipple's disease. During the hospital course, the patient improved with intravenous (IV) ceftriaxone.
  • Publisher: United States: Cureus Inc
  • Language: English
  • Identifier: ISSN: 2168-8184
    EISSN: 2168-8184
    DOI: 10.7759/cureus.1108
    PMID: 28439483
  • Source: PubMed Central
    ProQuest Central
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