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LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in human and mouse

Nucleic acids research, 2019-01, Vol.47 (D1), p.D140-D144 [Peer Reviewed Journal]

The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research. 2019 ;ISSN: 0305-1048 ;EISSN: 1362-4962 ;DOI: 10.1093/nar/gky1051 ;PMID: 30380072

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  • Title:
    LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in human and mouse
  • Author: Cheng, Liang ; Wang, Pingping ; Tian, Rui ; Wang, Song ; Guo, Qinghua ; Luo, Meng ; Zhou, Wenyang ; Liu, Guiyou ; Jiang, Huijie ; Jiang, Qinghua
  • Subjects: Animals ; Computational Biology - methods ; Database Issue ; Databases, Nucleic Acid ; Gene Expression Regulation ; Humans ; Mice ; RNA Interference ; RNA, Long Noncoding - genetics ; Software ; User-Computer Interface ; Web Browser
  • Is Part Of: Nucleic acids research, 2019-01, Vol.47 (D1), p.D140-D144
  • Description: Abstract Long non-coding RNAs (lncRNAs) play crucial roles in regulating gene expression, and a growing number of researchers have focused on the identification of target genes of lncRNAs. However, no online repository is available to collect the information on target genes regulated by lncRNAs. To make it convenient for researchers to know what genes are regulated by a lncRNA of interest, we developed a database named lncRNA2Target to provide a comprehensive resource of lncRNA target genes in 2015. To update the database this year, we retrieved all new lncRNA–target relationships from papers published from 1 August 2014 to 30 April 2018 and RNA-seq datasets before and after knockdown or overexpression of a specific lncRNA. LncRNA2Target database v2.0 provides a web interface through which its users can search for the targets of a particular lncRNA or for the lncRNAs that target a particular gene, and is freely accessible at http://123.59.132.21/lncrna2target.
  • Publisher: England: Oxford University Press
  • Language: English
  • Identifier: ISSN: 0305-1048
    EISSN: 1362-4962
    DOI: 10.1093/nar/gky1051
    PMID: 30380072
  • Source: Oxford Journals website
    Geneva Foundation Free Medical Journals at publisher websites
    MEDLINE
    PubMed Central
    DOAJ Directory of Open Access Journals

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