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Natural course of non-center-involving diabetic macular edema progression in patients under initial observation

Indian journal of ophthalmology, 2024-02, Vol.72 (2), p.236-239 [Peer Reviewed Journal]

Copyright © 2023 Copyright: © 2023 Indian Journal of Ophthalmology. ;COPYRIGHT 2024 Medknow Publications and Media Pvt. Ltd. ;2024. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 0301-4738 ;EISSN: 1998-3689 ;DOI: 10.4103/IJO.IJO_2182_22 ;PMID: 38153973

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Title:
Natural course of non-center-involving diabetic macular edema progression in patients under initial observation
Author: Pradhana, Divya ; Priya, N Swathi ; Manayath, George J ; Kulkarni, Sucheta ; Behera, Umesh C ; Agarwal, Tushar ; Agarwal, Manisha ; Shah, Shalin ; Giridhar, A ; Surya, Janani ; Ramasamy, Kim ; Vignesh, T P ; Shoba, Sivaprasad ; Bhende, Muna ; Raman, Rajiv
Subjects: Acuity ; Care and treatment ; Child, Preschool ; cidme ; cst ; Development and progression ; Diabetes ; Diabetes mellitus (non-insulin dependent) ; Diabetes Mellitus, Type 2 - complications ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes therapy ; Diabetic retinopathy ; Diabetic Retinopathy - complications ; Diabetic Retinopathy - diagnosis ; Diabetic Retinopathy - epidemiology ; Dropsy ; Edema ; Electronic medical records ; Evaluation ; Evidence-based medicine ; Eye diseases ; Health risk assessment ; Humans ; Intravitreal Injections ; Macular Edema - diagnosis ; Macular Edema - drug therapy ; Macular Edema - etiology ; Medical research ; Medicine, Experimental ; ncidme ; Patients ; Retrospective Studies ; Risk factors ; Statistical analysis ; Tomography, Optical Coherence ; Type 2 diabetes ; Visual Acuity
Is Part Of: Indian journal of ophthalmology, 2024-02, Vol.72 (2), p.236-239
Description: We aim to report the natural course of non-center involving diabetic macular edema (NCIDME) progression to center involving diabetic macular edema (CIDME) and associated risk factors. This is a multicenter retrospective comparative study. Data was collected from electronic medical records from 8 centers in India covering. We included patients with type 2 diabetes above 18 years of age with treatment-naïve NCIDME on OCT and best-corrected visual acuity at baseline of 6/12 or better who were under observation for NCIDME and had 2 years follow-up data. Out of 72 patients with NCIDME, 26.38% patients progressed to CI DME by 2 years, and the visit wise proportion was 11.11% at 6 months, 7% at 1st year and 8.3% at 2 years. The change in CST was statistically significant at 2 years in patients who developed CIDME, the mean difference was 137.73 ± 48.56 microns p = 0.045. Duration of diabetes mellitus > 10 years was the only risk factor for conversion to CIDME. A quarter of eyes with NCIDME developed CIDME and 15% progressed from NPDR to PDR by 2 years, highlighting the disease burden in these patients with NCIDME.
Publisher: India: Medknow Publications and Media Pvt. Ltd
Language: English
Identifier: ISSN: 0301-4738
EISSN: 1998-3689
DOI: 10.4103/IJO.IJO_2182_22
PMID: 38153973
Source: Freely Accessible Journals
MEDLINE
PubMed Central
Medknow Medical Journals (Open access)
ProQuest Central
DOAJ Directory of Open Access Journals

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Natural course of non-center-involving diabetic macular edema progression in patients under initial observation

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