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23 Performance of the grace 2.0 score in patients with type 1 and type 2 myocardial infarction

Heart (British Cardiac Society), 2020-07, Vol.106 (Suppl 2), p.A17-A17 [Peer Reviewed Journal]

Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ. ;2020 Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ. ;ISSN: 1355-6037 ;EISSN: 1468-201X ;DOI: 10.1136/heartjnl-2020-BCS.23

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  • Title:
    23 Performance of the grace 2.0 score in patients with type 1 and type 2 myocardial infarction
  • Author: Hung, John ; Roos, Andreas ; Kadesjo, Erik ; McAllister, David ; Shah, Anoop SV ; Anand, Atul ; Strachan, Fiona E ; Fox, Keith AA ; Mills, Nicholas L ; Holzmann, Martin ; Chapman, Andrew R
  • Subjects: Health risk assessment ; Heart attacks
  • Is Part Of: Heart (British Cardiac Society), 2020-07, Vol.106 (Suppl 2), p.A17-A17
  • Description: IntroductionThe Global Registry of Acute Coronary Events (GRACE) score was developed to evaluate risk in patients with myocardial infarction. However, its performance in type 2 myocardial infarction is uncertain.MethodsIn two cohorts of consecutive patients with suspected acute coronary syndrome from ten hospitals in Scotland (n=48,282) and a tertiary care hospital in Sweden (n=22,589), we calculated the GRACE 2.0 score to estimate death at one year. Discrimination was evaluated by the area under the receiver-operator-curve (AUC), and compared for those with an adjudicated diagnosis of type 1 and type 2 myocardial infarction using DeLong’s test.ResultsType 1 myocardial infarction was diagnosed in 4,981 (10%) and 1,080 (5%) patients in Scotland and Sweden, respectively. At one year, 720 (15%) and 112 (10%) patients died with an AUC for the GRACE score of 0.83 (95% confidence interval [CI] 0.82 to 0.85) and 0.85 (95% CI 0.81 to 0.89). Type 2 myocardial infarction occurred in 1,121 (2%) and 247 (1%) patients in Scotland and Sweden respectively, with 258 (23%) and 57 (23%) deaths at one year. The AUC was 0.73 (95% CI 0.70 to 0.77) and 0.73 (95% CI 0.66 to 0.81) in type 2 myocardial infarction, which was lower than for type 1 myocardial infarction in both cohorts (P<0.001 and P=0.008, respectively).Abstract 23 Figure 1ConclusionsThe GRACE score provided good discrimination for all-cause death at one year in patients with type 1 myocardial infarction, and moderate discrimination for those with type 2 myocardial infarction.Conflict of InterestNone
  • Publisher: London: BMJ Publishing Group LTD
  • Language: English
  • Identifier: ISSN: 1355-6037
    EISSN: 1468-201X
    DOI: 10.1136/heartjnl-2020-BCS.23
  • Source: AUTh Library subscriptions: ProQuest Central
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