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Hereditary Angioedema

The New England journal of medicine, 2020-03, Vol.382 (12), p.1136-1148 [Peer Reviewed Journal]

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Title:
Hereditary Angioedema
Author: Busse, Paula J ; Christiansen, Sandra C
Longo, Dan L ; Longo, Dan L.
Subjects: Abdomen ; Adult ; Angioedema ; Angioedemas, Hereditary - diagnosis ; Angioedemas, Hereditary - drug therapy ; Angioedemas, Hereditary - physiopathology ; Angioneurotic edema ; Antibodies, Monoclonal, Humanized - therapeutic use ; Antifibrinolytic Agents - therapeutic use ; Bradykinin ; Care and treatment ; Complement Activation - physiology ; Complement C1 Inhibitor Protein - metabolism ; Complement C1 Inhibitor Protein - therapeutic use ; Complement component C1 ; Complications and side effects ; Development and progression ; Edema ; FDA approval ; Female ; Genetic disorders ; Genetic Testing ; Humans ; Kallikrein ; Mutation ; Pain ; Patients ; Permeability ; Progestins - therapeutic use ; Prophylaxis ; Proteins ; Quality of life ; Rare diseases
Is Part Of: The New England journal of medicine, 2020-03, Vol.382 (12), p.1136-1148
Description: Hereditary angioedema is a rare genetic disease that may include recurrent attacks of cutaneous angioedema, severe abdominal pain, and airway compromise. Prophylaxis and treatment include C1 inhibitor replacement and inhibition of the kallikrein and bradykinin pathways.
Publisher: United States: Massachusetts Medical Society
Language: English
Identifier: ISSN: 0028-4793
EISSN: 1533-4406
DOI: 10.1056/NEJMra1808012
PMID: 32187470
Source: ProQuest One Psychology
MEDLINE
ProQuest Central

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