skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Search type Index

The Relationship Between Adiponectin Serum Level and Coronary Artery Disease in Type 2 Diabetic Patients Adiponectin and CAD

Acta medica Iranica, 2021-01, Vol.59 (3), p.142 [Peer Reviewed Journal]

2021. This work is published under https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 0044-6025 ;EISSN: 1735-9694 ;DOI: 10.18502/acta.v59i3.5784

Full text available

Citations Cited by
  • Title:
    The Relationship Between Adiponectin Serum Level and Coronary Artery Disease in Type 2 Diabetic Patients Adiponectin and CAD
  • Author: Zahra Mazloum Khorasani ; Choobkar, Saeed ; Ramin Khameneh Bagheri ; AkbariRad, Mina ; Firoozi, Abdollah
  • Subjects: Cardiovascular disease ; Coronary vessels ; Diabetes ; Vein & artery diseases
  • Is Part Of: Acta medica Iranica, 2021-01, Vol.59 (3), p.142
  • Description: Adiponectin is an adipocytokine that has a higher serum level in healthy people. In type 2 diabetes, insulin resistance, hypertension, MI, and dyslipidemia, the serum level of adiponectin is lower than 4 µg/mL. Adiponectin is proved to have a protective role against atherosclerotic changes where its low serum levels in type 2 diabetes can lead to the progression of atherosclerotic lesions. In this study, we aimed to survey the possible effects of adiponectin in the development of coronary artery disease in type 2 diabetics. Thirty diabetic cases with coronary artery disease, 30 diabetic cases without known coronary artery disease, and a group of 30 healthy volunteers, all of them were between 18-65-year-old, were entered our study. We gathered demographic data by performing a physical examination followed by filling a checklist and a set of laboratory tests. All the groups were sex and age-matched (P=0.284 and P=0.163 respectively). CAD group had the lowest HBA1C (P<0.001). Both LDL and HDL were also lower in the CAD group (P<0.001). Adiponectin was also lower in the CAD group when compared to other groups (P<0.008) or when compared with only normal diabetics (P<0.002). We found a correlation between adiponectin and HDL (r=0.348, P=0.008), suggesting each unit of reduction in serum level of adiponectin could increase the chance of coronary artery disease by 38% in diabetics. In this study, we showed that the lower serum level of adiponectin is correlated with an increased risk of coronary artery disease in type 2 diabetics.
  • Publisher: Tehran: Tehran University of Medical Sciences
  • Language: English;French
  • Identifier: ISSN: 0044-6025
    EISSN: 1735-9694
    DOI: 10.18502/acta.v59i3.5784
  • Source: GFMER Free Medical Journals
    ProQuest Central
    DOAJ Directory of Open Access Journals
Back to results list
INSPIRE LIBRARY - TON DUC THANG UNIVERSITY (84-028) 37 755 057 Feedback
19 Nguyen Huu Tho St. Dist.7, HCM thuvien@tdtu.edu.vn

Copyright © 2017 INSPIRE LIBRARY - TON DUC THANG UNIVERSITY

Searching Remote Databases, Please Wait