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Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes

BMJ, 2010-03, Vol.340 (7752), p.907-911 [Peer Reviewed Journal]

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Title:
Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes
Author: Lévesque, Linda E ; Hanley, James A ; Kezouh, Abbas ; Suissa, Samy
Subjects: Bias ; Cohort Studies ; Design analysis ; Diabetes ; Diabetes Mellitus - prevention & control ; Disease Progression ; Dopamine ; Drugs ; Epidemiology ; Gastrointestinal agents ; Health risk assessment ; Heart attacks ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use ; Insulin ; Medical research ; Medical treatment ; Older adults ; Pharmacoepidemiology ; Research methods ; RESEARCH METHODS & REPORTING ; Statins ; Time dependence ; Time Factors
Is Part Of: BMJ, 2010-03, Vol.340 (7752), p.907-911
Description: Immortal time in observational studies can bias the results in favour of the treatment group, but it is not difficult to identify and avoid
Publisher: England: British Medical Journal Publishing Group
Language: English
Identifier: ISSN: 0959-8138
ISSN: 0959-8146
EISSN: 1468-5833
EISSN: 1756-1833
DOI: 10.1136/bmj.b5087
PMID: 20228141
CODEN: BMJOAE
Source: MEDLINE
Alma/SFX Local Collection
ProQuest Central

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