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Depression And Anxiety In Patients With Juvenile Idiopathic Arthritis: Current Insights And Impact On Quality Of Life, A Systematic Review

Open access rheumatology: research and reviews, 2019-11, Vol.11, p.237-252 [Peer Reviewed Journal]

2019 Fair et al. ;COPYRIGHT 2019 Dove Medical Press Limited ;COPYRIGHT 2019 Dove Medical Press Limited ;2019. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 Fair et al. 2019 Fair et al. ;ISSN: 1179-156X ;EISSN: 1179-156X ;DOI: 10.2147/OARRR.S174408 ;PMID: 31807093

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  • Title:
    Depression And Anxiety In Patients With Juvenile Idiopathic Arthritis: Current Insights And Impact On Quality Of Life, A Systematic Review
  • Author: Fair, Danielle C ; Rodriguez, Martha ; Knight, Andrea M ; Rubinstein, Tamar B
  • Subjects: Anxieties ; Anxiety ; Arthritis ; autoimmune disease ; Care and treatment ; Child health ; Childhood ; Children ; Children & youth ; Chronic diseases ; Chronic diseases in children ; Chronic illnesses ; Diseases ; Families & family life ; Health aspects ; Hospitals ; Librarians ; Lupus ; Medical research ; Medicine, Experimental ; Mental depression ; Mental disorders ; Mental health ; mood disorder ; Pain ; Pediatric diseases ; pediatric rheumatology ; Pediatrics ; Population ; Quality of life ; Review ; Rheumatoid arthritis ; Rheumatology ; Studies ; Systematic review ; Teenagers ; Youth
  • Is Part Of: Open access rheumatology: research and reviews, 2019-11, Vol.11, p.237-252
  • Description: Depression and anxiety are prevalent in children with rheumatologic diseases, including juvenile idiopathic arthritis (JIA). However, prevalence rates and the relationship with disease outcomes, including quality of life are conflicting in the early literature. To review the current literature, determine gaps in our knowledge, and identify areas in need of further investigation, we conducted a systematic review of studies examining depression and anxiety symptoms among children with JIA and the impact these symptoms may have on disease outcomes and quality of life. Six electronic databases were searched up until January 2019. Of 799 potential articles, 60 articles were included with the main focus on 28 articles from 2009 to 2019, to concentrate on the most current evidence. We found that JIA patients experience symptoms of depression and anxiety similar to other childhood chronic diseases and at higher rates than in healthy children. Patients who experience these symptoms have worse quality of life, with some evidence pointing to depression and anxiety symptoms having a greater impact on quality of life than other disease features, such as active joint count. Family members of JIA patients experience high rates of anxiety and depression symptoms which may impact their child's mental health and pain symptoms related to JIA. Conflicting reports of associations between depression/anxiety symptoms and disease features/disease outcomes and a paucity of longitudinal studies investigating the impact of treatment on mental health symptoms indicate areas in need of further research to effectively identify patients at greatest risk of depression and anxiety and to better understand how to treat and prevent these symptoms in youth with JIA. Family mental health should also be considered in investigations concerning mental health and disease outcomes of children with JIA.
  • Publisher: New Zealand: Dove Medical Press Limited
  • Language: English
  • Identifier: ISSN: 1179-156X
    EISSN: 1179-156X
    DOI: 10.2147/OARRR.S174408
    PMID: 31807093
  • Source: Open Access: PubMed Central
    DOAJ Directory of Open Access Journals
    Geneva Foundation Free Medical Journals at publisher websites
    AUTh Library subscriptions: ProQuest Central
    Dove Press Free

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