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Researching COVID to enhance recovery

PloS one, 2023-12, Vol.18 (12), p.e0285351 [Peer Reviewed Journal]

COPYRIGHT 2023 Public Library of Science ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0285351

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Title:
Researching COVID to enhance recovery
Author: Metz, Torri D ; Clifton, Rebecca G ; Gallagher, Richard ; Gross, Rachel S ; Horwitz, Leora I ; Jacoby, Vanessa L ; Martin-Herz, Susanne P ; Peralta-Carcelen, Myriam ; Reeder, Harrison T ; Beamon, Carmen J ; Chan, James ; Chang, A. Ann ; Costantine, Maged M ; Fitzgerald, Megan L ; Foulkes, Andrea S ; Gibson, Kelly S ; Güthe, Nick ; Habli, Mounira ; Hackney, David N ; Hoffman, Matthew K ; Hoffman, M. Camille ; Hughes, Brenna L ; Katz, Stuart D ; Laleau, Victoria ; Mallett, Gail ; Mendez-Figueroa, Hector ; Monzon, Vanessa ; Palatnik, Anna ; Palomares, Kristy T. S ; Parry, Samuel ; Pettker, Christian M ; Plunkett, Beth A ; Poppas, Athena ; Reddy, Uma M ; Rouse, Dwight J ; Saade, George R ; Sandoval, Grecio J ; Schlater, Shannon M ; Sciurba, Frank C ; Simhan, Hyagriv N ; Skupski, Daniel W ; Sowles, Amber ; Thaweethai, Tanayott ; Thomas, Gelise L ; Thorp, John M ; Tita, Alan T ; Weiner, Steven J ; Weigand, Samantha ; Yee, Lynn M ; Flaherman, Valerie J
Subjects: Health aspects ; Pregnant women
Is Part Of: PloS one, 2023-12, Vol.18 (12), p.e0285351
Description: Importance RECOVER-Pregnancy cohort is a combined prospective and retrospective cohort that proposes to enroll 2,300 individuals with a pregnancy during the COVID-19 pandemic and their offspring exposed and unexposed in utero, including single and multiple gestations. Enrollment will occur both in person at 27 sites through the Eunice Kennedy Shriver National Institutes of Health Maternal-Fetal Medicine Units Network and remotely through national recruitment by the study team at the University of California San Francisco (UCSF). Adults with and without SARS-CoV-2 infection during pregnancy are eligible for enrollment in the pregnancy cohort and will follow the protocol for RECOVER-Adult including validated screening tools, laboratory analyses and symptom questionnaires followed by more in-depth phenotyping of PASC on a subset of the overall cohort. Offspring exposed and unexposed in utero to SARS-CoV-2 maternal infection will undergo screening tests for neurodevelopment and other health outcomes at 12, 18, 24, 36 and 48 months of age. Blood specimens will be collected at 24 months of age for SARS-CoV-2 antibody testing, storage and anticipated later analyses proposed by RECOVER and other investigators. RECOVER-Pregnancy will address whether having SARS-CoV-2 during pregnancy modifies the risk factors, prevalence, and phenotype of PASC. The pregnancy cohort will also establish whether there are increased risks of adverse long-term outcomes among children exposed in utero.
Publisher: Public Library of Science
Language: English
Identifier: ISSN: 1932-6203
EISSN: 1932-6203
DOI: 10.1371/journal.pone.0285351
Source: Public Library of Science (PLoS) Journals Open Access
Geneva Foundation Free Medical Journals at publisher websites
AUTh Library subscriptions: ProQuest Central
PubMed Central
DOAJ Directory of Open Access Journals

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Researching COVID to enhance recovery

COPYRIGHT 2023 Public Library of Science ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0285351

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