skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Search type Index

Traditional Japanese apricot (Prunus mume) induces osteocalcin in osteoblasts

Bioscience, biotechnology, and biochemistry, 2022-03, Vol.86 (4), p.528-534 [Peer Reviewed Journal]

The Author(s) 2022. Published by Oxford University Press on behalf of Japan Society for Bioscience, Biotechnology, and Agrochemistry. ;ISSN: 1347-6947 ;EISSN: 1347-6947 ;DOI: 10.1093/bbb/zbac013 ;PMID: 35150233

Full text available

Citations Cited by
  • Title:
    Traditional Japanese apricot (Prunus mume) induces osteocalcin in osteoblasts
  • Author: Nomura, Sachiko ; Kono, Ryohei ; Imaoka, Masakazu ; Tazaki, Fumie ; Okuno, Yoshiharu ; Utsunomiya, Hirotoshi ; Takeda, Masatoshi ; Nakamura, Misa
  • Subjects: Fruit - metabolism ; Humans ; Middle Aged ; Osteoblasts - metabolism ; Osteocalcin - genetics ; Plant Extracts - metabolism ; Plant Extracts - pharmacology ; Prunus ; Prunus armeniaca
  • Is Part Of: Bioscience, biotechnology, and biochemistry, 2022-03, Vol.86 (4), p.528-534
  • Description: The fruit of Prunus mume (ume, also known as Japanese apricot) has been used as a functional food in Japan since ancient times. We previously reported that ume stimulates the differentiation of preosteoblastic cells. Osteocalcin (OCN) is secreted by osteoblasts, and there is known association with glucolipid metabolism and cognitive function. This study sought to clarify the relationship between ume extracts and OCN production both in vitro and in vivo. Alkaline phosphatase activity and OCN level in the ethyl acetate extracts of ume-treated extracts were significantly increased in preosteoblast MC3T3-E1 cells compared with the control group. In human study, serum OCN level was significantly higher in the high ume intake group than in the low intake group in community-dwelling participants over 60 years old. These results suggest that ume has the potential to upregulated OCN production both in vitro and in vivo.
  • Publisher: England
  • Language: English
  • Identifier: ISSN: 1347-6947
    EISSN: 1347-6947
    DOI: 10.1093/bbb/zbac013
    PMID: 35150233
  • Source: Geneva Foundation Free Medical Journals at publisher websites
    MEDLINE
Back to results list
INSPIRE LIBRARY - TON DUC THANG UNIVERSITY (84-028) 37 755 057 Feedback
19 Nguyen Huu Tho St. Dist.7, HCM thuvien@tdtu.edu.vn

Copyright © 2017 INSPIRE LIBRARY - TON DUC THANG UNIVERSITY

Searching Remote Databases, Please Wait