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HMU Fluorinze Mouthwash Enhances Enamel Remineralization: An In Vitro Study

Open access Macedonian journal of medical sciences, 2019-12, Vol.7 (24), p.4319-4323

Copyright: © 2019 Vo Truong Nhu Ngoc, Kimberly Mathieu Coulton, Nguyen Thu Tra, Nguyen Ha My, Phi Thi Quynh Huong, Tong Minh Son, Le Quynh Anh, Luu Quang Thuy, Tran Tuan Anh, Thien Chu Dinh, Chu Dinh Toi. ;Copyright: © 2019 Vo Truong Nhu Ngoc, Kimberly Mathieu Coulton, Nguyen Thu Tra, Nguyen Ha My, Phi Thi Quynh Huong, Tong Minh Son, Le Quynh Anh, Luu Quang Thuy, Tran Tuan Anh, Thien Chu Dinh, Chu Dinh Toi. 2019 ;ISSN: 1857-9655 ;EISSN: 1857-9655 ;DOI: 10.3889/oamjms.2019.383 ;PMID: 32215086

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  • Title:
    HMU Fluorinze Mouthwash Enhances Enamel Remineralization: An In Vitro Study
  • Author: Ngoc, Vo Truong Nhu ; Coulton, Kimberly Mathieu ; Tra, Nguyen Thu ; My, Nguyen Ha ; Huong, Phi Thi Quynh ; Son, Tong Minh ; Anh, Le Quynh ; Thuy, Luu Quang ; Anh, Tran Tuan ; Dinh, Thien Chu ; Toi, Chu Dinh
  • Subjects: Basic and Clinical Medical Researches in Vietnam
  • Is Part Of: Open access Macedonian journal of medical sciences, 2019-12, Vol.7 (24), p.4319-4323
  • Description: Fluoride therapy has long been used extensively to prevent dental caries. Fluoride appears in a variety of dental care products such as mouth rinses, dentifrices, gels, etc. HMU Fluorinze is the first mouthwash containing fluoride in Vietnam. This research was conducted to evaluate the efficacy of HMU Fluorinze mouthwash on remineralizing enamel in laboratory conditions. 20 third molar teeth were cleaned and covered with nail polish, except for a 3 x 3 mm square on their buccal surfaces. These teeth underwent two steps: demineralization using Coca-cola and remineralization for 20 daysusing standard calcifying solution (control group) and standard calcifying solution + HMU Fluorinze mouthwash 2 times/day (experimental group). The index measured of enamel structure after demineralization and remineralization was assessed by a DIAGNOdent pen 2190. The indices measured of the control group and experimental group at baseline were 3.65 ± 0.76 and 3.35 ± 0.64 respectively. After demineralization the control group measured 21.78 ± 4.48 and the experimental group, 20.25 ± 2.26. Following remineralization, the control group scores were 6.30 ± 1.03 and the experimental group, 3.90 ± 1.24, demonstrating statistical significance (p < 0.01) between the two groups. After 20 days, the results for the experimental group did not differ from the original results (p = 0.272), in contrast with the control group (p < 0.01). Results show that HMU Fluorinze mouthwash is better at remineralizing than standard calcifying solution.
  • Publisher: North Macedonia: Republic of Macedonia
  • Language: English
  • Identifier: ISSN: 1857-9655
    EISSN: 1857-9655
    DOI: 10.3889/oamjms.2019.383
    PMID: 32215086
  • Source: PubMed Central
    ROAD: Directory of Open Access Scholarly Resources

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