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Treatment And Prevention for female Sex workers in South Africa: protocol for the TAPS Demonstration Project

BMJ open, 2016-09, Vol.6 (9), p.e011595-e011595 [Peer Reviewed Journal]

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing ;Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ 2016 This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ 2016 ;EISSN: 2044-6055 ;DOI: 10.1136/bmjopen-2016-011595 ;PMID: 27678533

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  • Title:
    Treatment And Prevention for female Sex workers in South Africa: protocol for the TAPS Demonstration Project
  • Author: Gomez, Gabriela B ; Eakle, Robyn ; Mbogua, Judie ; Akpomiemie, Godspower ; Venter, W D Francois ; Rees, Helen
  • Subjects: Central business districts ; Community ; Criminalization ; Drug therapy ; HIV ; HIV/AIDS ; Human immunodeficiency virus ; Infections ; Intervention ; Population ; Prevention ; Reproductive health ; Sex industry ; Strategic planning ; Tuberculosis ; Workers
  • Is Part Of: BMJ open, 2016-09, Vol.6 (9), p.e011595-e011595
  • Description: Updated guidelines from the WHO recommend antiretroviral treatment for adults with HIV at any CD4 count and daily oral pre-exposure prophylaxis (PrEP) for people at substantial risk of HIV infection. However, implementation challenges may hinder the ability of programmes to translate these recommendations into successful practice. This demonstration project is the first to integrate PrEP and immediate treatment (ITx) for female sex workers (FSWs) in South Africa to answer operational research questions. This is a prospective cohort study where the main outcome is retention at 12 months. The study population is recruited into two arms across two urban sites: (1) PrEP for HIV-negative FSWs (n=400) and (2) ITx for HIV-positive FSWs with CD4 greater than national guidelines (n=300). We investigate process and other health indicators, uptake and use of PrEP and ITx through qualitative research, and evaluate cost-effectiveness analysis combined with estimates of impact through epidemiological modelling. The Treatment And Prevention for female Sex workers in South Africa (TAPS) Project was designed as an implementation study before emtricitabine/tenofovir disoproxil fumarate was licenced as an indication for PrEP in South Africa. Therefore, clinical trial requirements for ethical and South African Medicines Control Council approvals were followed. Results will be disseminated to participants, local health officials and other stakeholders, as well as in peer-reviewed journals and at conferences.
  • Publisher: England: BMJ Publishing Group LTD
  • Language: English
  • Identifier: EISSN: 2044-6055
    DOI: 10.1136/bmjopen-2016-011595
    PMID: 27678533
  • Source: ProQuest One Psychology
    BMJ Open Access Journals
    GFMER Free Medical Journals
    PubMed Central
    ROAD: Directory of Open Access Scholarly Resources
    ProQuest Central
    DOAJ Directory of Open Access Journals
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