skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Search type Index

The importance of patient-reported outcomes in clinical trials and strategies for future optimization

Patient related outcome measures, 2018-01, Vol.9, p.353-367 [Peer Reviewed Journal]

COPYRIGHT 2018 Dove Medical Press Limited ;COPYRIGHT 2018 Dove Medical Press Limited ;2018. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2018 Mercieca-Bebber et al. This work is published and licensed by Dove Medical Press Limited 2018 ;ISSN: 1179-271X ;EISSN: 1179-271X ;DOI: 10.2147/prom.s156279 ;PMID: 30464666

Full text available

  • Title:
    The importance of patient-reported outcomes in clinical trials and strategies for future optimization
  • Author: Mercieca-Bebber, Rebecca ; King, Madeleine T ; Calvert, Melanie J ; Stockler, Martin R ; Friedlander, Michael
  • Subjects: Biomedical research ; Cancer ; Clinical trials ; clinical trials as topic ; Medical research ; Medicine, Experimental ; Oncology ; Patient-reported outcomes ; Patients ; Product development ; Product reviews ; Quality of life ; research practices ; Review ; Ruxolitinib ; trial conduct
  • Is Part Of: Patient related outcome measures, 2018-01, Vol.9, p.353-367
  • Description: Patient-reported outcomes (PROs) can be included in clinical trials as primary or secondary endpoints and are increasingly recognized by regulators, clinicians, and patients as valuable tools to collect patient-centered data. PROs provide unique information on the impact of a medical condition and its treatment from the patient's perspective; therefore, PROs can be included in clinical trials to ensure the impact of a trial intervention is comprehensively assessed. This review first discusses examples of how PRO endpoints have added value to clinical trial interpretation. Second, it describes the problems with current practices in designing, implementing, and reporting PRO studies, and how these problems may be addressed by complying with guidance for protocol development, selecting appropriate PRO measures to match clinically motivated PRO hypotheses, minimizing the rates of avoidable missing PRO data, analyzing and interpreting PRO data, and transparently reporting PRO findings.
  • Publisher: New Zealand: Dove Medical Press Limited
  • Language: English
  • Identifier: ISSN: 1179-271X
    EISSN: 1179-271X
    DOI: 10.2147/prom.s156279
    PMID: 30464666
  • Source: Geneva Foundation Free Medical Journals at publisher websites
    PubMed Central
    ROAD: Directory of Open Access Scholarly Resources
    ProQuest Central
    DOAJ Directory of Open Access Journals
    Dove Press Free
Back to results list
INSPIRE LIBRARY - TON DUC THANG UNIVERSITY (84-028) 37 755 057 Feedback
19 Nguyen Huu Tho St. Dist.7, HCM thuvien@tdtu.edu.vn

Copyright © 2017 INSPIRE LIBRARY - TON DUC THANG UNIVERSITY

Searching Remote Databases, Please Wait