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A novel plasmid carrying carbapenem-resistant gene [bla.sub.KPC-2] in Pseudomonas aeruginosa

Infection and drug resistance, 2019-05, p.1285 [Peer Reviewed Journal]

COPYRIGHT 2019 Dove Medical Press Limited ;COPYRIGHT 2019 Dove Medical Press Limited ;ISSN: 1178-6973 ;EISSN: 1178-6973 ;DOI: 10.2147/IDR.S196390

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  • Title:
    A novel plasmid carrying carbapenem-resistant gene [bla.sub.KPC-2] in Pseudomonas aeruginosa
  • Author: Hu, Yan-Yan ; Wang, Qi ; Sun, Qiao-Ling ; Chen, Gong-Xiang ; Zhang, Rong
  • Subjects: Infection ; Medical schools ; Mortality ; Novels
  • Is Part Of: Infection and drug resistance, 2019-05, p.1285
  • Description: A carbapenem-resistant Pseudomonas aeruginosa strain PA1011 (ST463) was isolated from a patient in a surgical intensive care unit. PCR detection showed that PA1011 carried the [bla.sub.KPC-2] gene. A plasmid was isolated and sequenced using the Illumina NextSeq 500 and PacBio RSII sequencing platforms. The plasmid was named pPA1011 and carried the carbapenem-resistant gene [bla.sub.KPC-2] pPA1011 was a 62,793 bp in length with an average G+C content of 58.8%. It was identified as a novel plasmid and encoded a novel genetic environment of [bla.sub.KPC-2] gene (AIS6-Tn3-ISKpn8-[bla.sub.KPC-2]-ISKpn6-IS26). Keywords: plasmid, genetic environment, KPC, ST463, Pseudomonas aeruginosa
  • Publisher: Dove Medical Press Limited
  • Language: English
  • Identifier: ISSN: 1178-6973
    EISSN: 1178-6973
    DOI: 10.2147/IDR.S196390
  • Source: PubMed Central (Open access)
    Geneva Foundation Free Medical Journals at publisher websites
    ROAD: Directory of Open Access Scholarly Resources
    ProQuest Central
    DOAJ Directory of Open Access Journals
    Dove Press Free
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