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Chlamydia trachomatis生殖器感染症のMinocycline内服による治療成績
感染症学雑誌, 1985/08/20, Vol.59(8), pp.824-830
日本感染症学会 ;ISSN: 0387-5911 ;EISSN: 1884-569X ;DOI: 10.11150/kansenshogakuzasshi1970.59.824
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Title:
Chlamydia trachomatis生殖器感染症のMinocycline内服による治療成績
Author:
小島, 弘敬
;
森, 忠三
Is Part Of:
感染症学雑誌, 1985/08/20, Vol.59(8), pp.824-830
Description:
Chlamydia trachomatis感染による男子尿道炎50例, 副睾丸炎5例, 女子子宮頸管炎5例の計60例に対するMinocyclineの効果について検討した. Cklamydia trachomatisの検出は, 抗Chlamydia trachomatis種特異性抗原に対するモノクローナル抗体を用いる蛍光抗体直接法により行った. Minocycline投与量は, 尿道炎に対しては1日200mgあるいは300mg, また副睾丸炎, 子宮頸管炎に対しては1日200mgであつた. Minocycline は Chlamydia trachomatisの感染による尿道炎, 副睾丸炎, 子宮頸管炎のいずれの症例に対しても有効であった. 副作用は, めまい, フラフラ感が認められたが, いずれも1日300mg投与症例であつた. C. tnachomwtisによる尿道炎, 子宮頚管炎の自覚症状は軽度で治療効果の判定の指標とはなりえず, 治療効果の判定はC. trachomatいsの陰性化及び他覚症状の消失によるべきであることを指摘した.
Publisher:
一般社団法人 日本感染症学会
Language:
Japanese
Identifier:
ISSN: 0387-5911
EISSN: 1884-569X
DOI: 10.11150/kansenshogakuzasshi1970.59.824
Source:
Alma/SFX Local Collection
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