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Childhood Incident Asthma and Traffic-Related Air Pollution at Home and School

Environmental health perspectives, 2010-07, Vol.118 (7), p.1021-1026 [Peer Reviewed Journal]

2015 INIST-CNRS ;COPYRIGHT 2010 National Institute of Environmental Health Sciences ;COPYRIGHT 2010 National Institute of Environmental Health Sciences ;Copyright National Institute of Environmental Health Sciences Jul 2010 ;2010 ;ISSN: 0091-6765 ;EISSN: 1552-9924 ;DOI: 10.1289/ehp.0901232 ;PMID: 20371422 ;CODEN: EVHPAZ

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Title:
Childhood Incident Asthma and Traffic-Related Air Pollution at Home and School
Author: McConnell, Rob ; Islam, Talat ; Shankardass, Ketan ; Jerrett, Michael ; Lurmann, Fred ; Gilliland, Frank ; Gauderman, Jim ; Avol, Ed ; Künzli, Nino ; Yao, Ling ; Peters, John ; Berhane, Kiros
Subjects: Air ; Air Pollutants - analysis ; Air Pollutants - toxicity ; Air pollution ; Asthma ; Asthma - chemically induced ; Asthma - epidemiology ; Asthma in children ; Biological and medical sciences ; California - epidemiology ; Child ; Children ; Children and travel ; Children's Health ; Chronic obstructive pulmonary disease, asthma ; Elementary school students ; Environment. Living conditions ; Environmental aspects ; Environmental Exposure ; Environmental pollutants toxicology ; Freeways ; Health aspects ; Homes ; Humans ; Medical sciences ; Models, Statistical ; Nitrogen Dioxide - analysis ; Nitrogen Dioxide - toxicity ; Ozone - analysis ; Ozone - toxicity ; Particulate Matter - analysis ; Particulate Matter - toxicity ; Pneumology ; Pollutants ; Pollution monitoring ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Retirement communities ; Risk Factors ; Roads ; Schools ; Toxicology ; Traffic estimation ; Vehicle Emissions - analysis ; Vehicle Emissions - toxicity ; Weather
Is Part Of: Environmental health perspectives, 2010-07, Vol.118 (7), p.1021-1026
Description: Background: Traffic-related air pollution has been associated with adverse cardiorespiratory effects, including increased asthma prevalence. However, there has been little study of effects of traffic exposure at school on new-onset asthma. Objectives: We evaluated the relationship of new-onset asthma with traffic-related pollution near homes and schools. Methods: Parent-reported physician diagnosis of new-onset asthma (n = 120) was identified during 3 years of follow-up of a cohort of 2,497 kindergarten and first-grade children who were asthma- and wheezing-free at study entry into the Southern California Children's Health Study. We assessed traffic-related pollution exposure based on a line source dispersion model of traffic volume, distance from home and school, and local meteorology. Regional ambient ozone, nitrogen dioxide (NO2), and particulate matter were measured continuously at one central site monitor in each of 13 study communities. Hazard ratios (HRs) for new-onset asthma were scaled to the range of ambient central site pollutants and to the residential interquartile range for each traffic exposure metric. Results: Asthma risk increased with modeled traffic-related pollution exposure from roadways near homes [HR 1.51; 95% confidence interval (CI), 1.25–1.82] and near schools (HR 1.45; 95% CI, 1.06–1.98). Ambient NO2 measured at a central site in each community was also associated with increased risk (HR 2.18; 95% CI, 1.18–4.01). In models with both NO2 and modeled traffic exposures, there were independent associations of asthma with traffic-related pollution at school and home, whereas the estimate for NO2 was attenuated (HR 1.37;95% CI, 0.69–2.71). Conclusions: Traffic-related pollution exposure at school and homes may both contribute to the development of asthma.
Publisher: Research Triangle Park, NC: National Institute of Environmental Health Sciences
Language: English
Identifier: ISSN: 0091-6765
EISSN: 1552-9924
DOI: 10.1289/ehp.0901232
PMID: 20371422
CODEN: EVHPAZ
Source: US Government Documents
MEDLINE
PubMed Central
ProQuest Central
DOAJ Directory of Open Access Journals

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Childhood Incident Asthma and Traffic-Related Air Pollution at Home and School

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