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0294 Job-exposure matrix addressing smoking in the nationwide danish occupational cohort, docx

Occupational and environmental medicine (London, England), 2017-08, Vol.74 (Suppl 1), p.A92 [Peer Reviewed Journal]

2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions ;Copyright: 2017 © 2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions ;ISSN: 1351-0711 ;EISSN: 1470-7926 ;DOI: 10.1136/oemed-2017-104636.242

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  • Title:
    0294 Job-exposure matrix addressing smoking in the nationwide danish occupational cohort, docx
  • Author: Petersen, Sesilje Bondo ; Flachs, Esben M ; Villadsen, Ebbe ; Prescott, Eva ; Tjønneland, Anne ; Osler, Merete ; Andersen, Ingelise ; Juel, Knud ; Budtz-Jørgensen, Esben ; Kolstad, Henrik A ; Schlünssen, Vivi ; Bonde, Jens Peter
  • Subjects: Breast cancer ; Cadmium ; Coefficient of variation ; Correlation coefficient ; Correlation coefficients ; Exposure ; Hospitals ; Mammography ; Mathematical analysis ; Medicine ; Occupational exposure ; Occupational health ; Public health ; Questionnaires ; Smoking ; Urine
  • Is Part Of: Occupational and environmental medicine (London, England), 2017-08, Vol.74 (Suppl 1), p.A92
  • Description: ObjectivesTo develop a job-exposure matrix (JEM) addressing smoking to allow for confounder adjustment in register-based occupational health studies. MethodsWe combined and harmonised questionnaire and interview data on smoking from several Danish cohort studies and surveys in the time-period 1981–2013 for 2 64 054 employees registered with a DISCO-88 code (the Danish version of ISCO-88) in the Danish nationwide JEM database, DOC*X. We modelled the probability of being a smoker, and the amount of smoking (g/d) among smokers. In mixed models, age and sex were included as fixed effects and DISCO as random effect for six different time-periods. ResultsThe proportion of smokers decreased linearly from 56% in 1981–90% to 19% after 2010, whereas the amount increased from 15.9 g/d in 1981 to 16.5 g/d in 1991–95, and then declined to 13.2 g/d after 2010. In general, the quality of the JEM increased by calendar year, as 23% and 71% of the DISCO-codes were represented in the first and latest time-period, respectively, on the most detailed 4 digit DISCO-level. This was also reflected in the calculated interclass correlation coefficient (ICC), which increased by calendar year. The within job-group variation was large relative to the between jobs variation, but the range between jobs was in general high, as the probability ranged from 6% to 40% and the amount from 8.0 to 19.5 g/d after 2010. ConclusionsWe succeeded addressing a smoking JEM with substantial variability between jobs, which may prove a useful tool for confounder adjustment in register-based occupational studies.
  • Publisher: London: BMJ Publishing Group LTD
  • Language: English
  • Identifier: ISSN: 1351-0711
    EISSN: 1470-7926
    DOI: 10.1136/oemed-2017-104636.242
  • Source: AUTh Library subscriptions: ProQuest Central
    Alma/SFX Local Collection
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