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Rhino-Orbital Mucormycosis Associated With COVID-19

Curēus (Palo Alto, CA), 2020-09, Vol.12 (9) [Peer Reviewed Journal]

Copyright © 2020, Mehta et al. This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Copyright © 2020, Mehta et al. 2020 Mehta et al. ;ISSN: 2168-8184 ;EISSN: 2168-8184 ;DOI: 10.7759/cureus.10726 ;PMID: 33145132

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  • Title:
    Rhino-Orbital Mucormycosis Associated With COVID-19
  • Author: Mehta, Salil ; Pandey, Abha
  • Subjects: Antibiotics ; Biopsy ; Coronaviruses ; COVID-19 ; Diabetes ; Disease ; Edema ; Foot diseases ; Fungal infections ; Infectious Disease ; Insulin ; Internal Medicine ; Lungs ; Magnetic resonance imaging ; Morbidity ; Mortality ; Nosocomial infections ; Ophthalmology ; Oxygen saturation ; Patients ; Pneumonia ; Severe acute respiratory syndrome coronavirus 2 ; Sinuses
  • Is Part Of: Curēus (Palo Alto, CA), 2020-09, Vol.12 (9)
  • Description: Coronavirus disease 2019 (COVID-19) infections may be associated with a wide range of bacterial and fungal co-infections. We report the case of a patient with COVID-19 infection, which, during the course of the treatment, developed rhino-orbital mucormycosis. A 60- year-old male patient, a longstanding diabetic, with a positive reverse-transcriptase polymerase chain reaction (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was admitted for treatment. He received parenteral meropenem and oral oseltamivir with parenteral methylprednisolone. Over the course of the admission, he developed signs of orbital cellulitis. Magnetic resonance imaging (MRI) of the brain, orbits, and paranasal sinuses, revealed soft tissue swelling in the right preseptal, malar, premaxillary and retrobulbar regions with paranasal sinusitis. A nasal biopsy revealed broad aseptate filamentous fungal hyphae suggestive of mucormycosis, which was confirmed on culture. Extensive use of steroids/monoclonal antibodies/broad-spectrum antibiotics may lead to the development/exacerbation of a preexisting fungal disease. Physicians should be aware of the possibility of secondary invasive fungal infections in patients with COVID-19 infection.
  • Publisher: Palo Alto: Cureus Inc
  • Language: English
  • Identifier: ISSN: 2168-8184
    EISSN: 2168-8184
    DOI: 10.7759/cureus.10726
    PMID: 33145132
  • Source: PubMed Central
    Coronavirus Research Database
    ProQuest Central
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