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Comparison of CaOH with MTA for Direct Pulp Capping: A PBRN Randomized Clinical Trial

Journal of dental research, 2013-07, Vol.92 (7_suppl), p.S16-S22 [Peer Reviewed Journal]

International & American Associations for Dental Research ;International & American Associations for Dental Research 2013 International & American Associations for Dental Research ;ISSN: 0022-0345 ;EISSN: 1544-0591 ;DOI: 10.1177/0022034513484336 ;PMID: 23690353

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Title:
Comparison of CaOH with MTA for Direct Pulp Capping: A PBRN Randomized Clinical Trial
Author: Hilton, T.J. ; Ferracane, J.L. ; Mancl, L. ; Baltuck, C. ; Barnes, C. ; Beaudry, D. ; Shao, J. ; Lubisich, E. ; Gilbert, A. ; Lowder, L.
Subjects: Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aluminum Compounds - therapeutic use ; Calcium Compounds - therapeutic use ; Calcium Hydroxide - therapeutic use ; Child ; Clinical Trials ; Community-Based Participatory Research ; Dental Pulp - physiology ; Dental Pulp Capping - methods ; Dental Pulp Exposure - therapy ; Dentin-Bonding Agents - chemistry ; Dentistry ; Drug Combinations ; Female ; Follow-Up Studies ; Glass Ionomer Cements - chemistry ; Humans ; Male ; Middle Aged ; Oxides - therapeutic use ; Pulp Capping and Pulpectomy Agents - therapeutic use ; Pulpotomy - methods ; Radiography, Bitewing ; Resin Cements - chemistry ; Root Canal Therapy ; Silicates - therapeutic use ; Tooth Extraction ; Treatment Outcome ; Young Adult
Is Part Of: Journal of dental research, 2013-07, Vol.92 (7_suppl), p.S16-S22
Description: This practice-based, randomized clinical trial evaluated and compared the success of direct pulp capping in permanent teeth with MTA (mineral trioxide aggregate) or CaOH (calcium hydroxide). Thirty-five practices in Northwest PRECEDENT were randomized to perform direct pulp caps with either CaOH (16 practices) or MTA (19 practices). Three hundred seventy-six individuals received a direct pulp cap with CaOH (n = 181) or MTA (n = 195). They were followed for up to 2 yrs at regular recall appointments, or as dictated by tooth symptoms. The primary outcomes were the need for extraction or root canal therapy. Teeth were also evaluated for pulp vitality, and radiographs were taken at the dentist’s discretion. The probability of failure at 24 mos was 31.5% for CaOH vs. 19.7% for MTA (permutation log-rank test, p = .046). This large randomized clinical trial provided confirmatory evidence for a superior performance with MTA as a direct pulp-capping agent as compared with CaOH when evaluated in a practice-based research network for up to 2 yrs (ClinicalTrials.gov NCT00812887).
Publisher: Los Angeles, CA: SAGE Publications
Language: English
Identifier: ISSN: 0022-0345
EISSN: 1544-0591
DOI: 10.1177/0022034513484336
PMID: 23690353
Source: MEDLINE
Alma/SFX Local Collection

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Comparison of CaOH with MTA for Direct Pulp Capping: A PBRN Randomized Clinical Trial

International & American Associations for Dental Research ;International & American Associations for Dental Research 2013 International & American Associations for Dental Research ;ISSN: 0022-0345 ;EISSN: 1544-0591 ;DOI: 10.1177/0022034513484336 ;PMID: 23690353

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