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Primary prevention aspirin among the elderly: challenges in translating trial evidence to the clinic

The British journal of cardiology, 2020-01, Vol.27 (1) [Peer Reviewed Journal]

Copyright © 2020 Medinews (Cardiology) Limited 2020 ;ISSN: 0969-6113 ;EISSN: 1753-4313 ;DOI: 10.5837/bjc.2020.007 ;PMID: 35747418

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  • Title:
    Primary prevention aspirin among the elderly: challenges in translating trial evidence to the clinic
  • Author: McEvoy, J William ; Keane, Michael ; Ng, Justin
  • Subjects: Primary Prevention
  • Is Part Of: The British journal of cardiology, 2020-01, Vol.27 (1)
  • Description: The ASPirin in Reducing Events in the Elderly trial (ASPREE) contributed important knowledge about primary cardiovascular disease (CVD) prevention among healthy older adults. The finding that daily low-dose aspirin (LDA) does not statistically prevent disability or CVD among adults aged over 70 years when compared with placebo, but does significantly increase risk of haemorrhage, immediately influenced clinical practice guidelines. In this article, we discuss nuances of the trial that may impact the extrapolation of the ASPREE trial results to the everyday individual clinical care of older adults.
  • Publisher: Medinews (Cardiology) Limited
  • Language: English
  • Identifier: ISSN: 0969-6113
    EISSN: 1753-4313
    DOI: 10.5837/bjc.2020.007
    PMID: 35747418
  • Source: PubMed Central
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