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Substitutability of menthol cigarette alternatives: a clinical trial

Tobacco control, 2023-11, p.tc-2023-058272 [Peer Reviewed Journal]

Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. ;2023 Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 0964-4563 ;EISSN: 1468-3318 ;DOI: 10.1136/tc-2023-058272 ;PMID: 37963771

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  • Title:
    Substitutability of menthol cigarette alternatives: a clinical trial
  • Author: Villanti, Andrea C ; Hinton, Alice ; Schulz, Jonathan A ; Erath, Tyler G ; Mehta, Toral ; Reed, Derek ; Tidey, Jennifer ; Businelle, Michael ; Wagener, Theodore L
  • Subjects: Addiction ; Adults ; Alternatives ; Bans ; Cigarettes ; Corporate profits ; Drug withdrawal ; Hand-rolled/RYO tobacco ; Marketing ; Menthol ; Nicotine ; Non-cigarette tobacco products ; Original research ; Public policy ; Questionnaires ; Smoke ; Smoking ; Substitutes ; Tobacco ; Word of mouth advertising
  • Is Part Of: Tobacco control, 2023-11, p.tc-2023-058272
  • Description: IntroductionThis study assessed the substitutability of plausible combustible menthol cigarette alternatives (MCAs) for usual brand menthol cigarettes (UBMCs) in adults who smoke menthol cigarettes.MethodsFollowing three in-lab sampling sessions, 80 adults aged 21–50 who smoke menthol cigarettes chose their preferred MCA: (1) a menthol roll-your-own cigarette (mRYO), (2) a menthol filtered little cigar (mFLC) or (3) a non-menthol cigarette (NMC). Participants were instructed to completely substitute their preferred MCA for their UBMC for 1 week and complete daily diaries documenting adherence and subjective effects. At the final lab visit, participants completed concurrent choice and cross-price elasticity tasks with their substitute product and UBMC as the comparator.ResultsMost (65%) participants chose mRYO as their preferred product, followed by NMC and mFLC. Adherence to MCA was high for all products across the week (range: 63%–88%). Positive subjective effects for mRYO decreased over time but remained numerically higher than the other MCA products; craving reduction also decreased for NMC across phases. In the progressive ratio task, participants chose their UBMC in 61.7% of choices; this did not differ by preferred MCA, although the median breakpoint was highest for mRYO and similar for mFLC and NMC. Cross-price elasticity comparing UBMC and the preferred product indicated high substitutability of each MCA at phase 3 (I values −0.70 to −0.82).Conclusions and relevancemRYOs were the most preferred MCA among the study products, but all MCAs were acceptable substitutes for UBMC using behavioural and economic measures in a short-term trial period.Trial registration number NCT04844762.
  • Publisher: England: BMJ Publishing Group Ltd
  • Language: English
  • Identifier: ISSN: 0964-4563
    EISSN: 1468-3318
    DOI: 10.1136/tc-2023-058272
    PMID: 37963771
  • Source: BMJ Open Access Journals
    Alma/SFX Local Collection
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