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Saturated Fats and Health: A Reassessment and Proposal for Food-Based Recommendations: JACC State-of-the-Art Review

Journal of the American College of Cardiology, 2020-08, Vol.76 (7), p.844 [Peer Reviewed Journal]

Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved. ;EISSN: 1558-3597 ;DOI: 10.1016/j.jacc.2020.05.077 ;PMID: 32562735

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Title:
Saturated Fats and Health: A Reassessment and Proposal for Food-Based Recommendations: JACC State-of-the-Art Review
Author: Astrup, Arne ; Magkos, Faidon ; Bier, Dennis M ; Brenna, J Thomas ; de Oliveira Otto, Marcia C ; Hill, James O ; King, Janet C ; Mente, Andrew ; Ordovas, Jose M ; Volek, Jeff S ; Yusuf, Salim ; Krauss, Ronald M
Subjects: Cardiometabolic Risk Factors ; Cardiovascular Diseases - metabolism ; Cardiovascular Diseases - mortality ; Cardiovascular Diseases - prevention & control ; Dietary Fats - metabolism ; Fatty Acids - metabolism ; Humans ; Recommended Dietary Allowances - trends ; Risk Assessment ; Stroke - epidemiology ; Stroke - metabolism ; Stroke - prevention & control
Is Part Of: Journal of the American College of Cardiology, 2020-08, Vol.76 (7), p.844
Description: The recommendation to limit dietary saturated fatty acid (SFA) intake has persisted despite mounting evidence to the contrary. Most recent meta-analyses of randomized trials and observational studies found no beneficial effects of reducing SFA intake on cardiovascular disease (CVD) and total mortality, and instead found protective effects against stroke. Although SFAs increase low-density lipoprotein (LDL) cholesterol, in most individuals, this is not due to increasing levels of small, dense LDL particles, but rather larger LDL particles, which are much less strongly related to CVD risk. It is also apparent that the health effects of foods cannot be predicted by their content in any nutrient group without considering the overall macronutrient distribution. Whole-fat dairy, unprocessed meat, and dark chocolate are SFA-rich foods with a complex matrix that are not associated with increased risk of CVD. The totality of available evidence does not support further limiting the intake of such foods.
Publisher: United States
Language: English
Identifier: EISSN: 1558-3597
DOI: 10.1016/j.jacc.2020.05.077
PMID: 32562735
Source: GFMER Free Medical Journals
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Saturated Fats and Health: A Reassessment and Proposal for Food-Based Recommendations: JACC State-of-the-Art Review

Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved. ;EISSN: 1558-3597 ;DOI: 10.1016/j.jacc.2020.05.077 ;PMID: 32562735

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