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Pregnancy and cardiovascular disease

Nature reviews cardiology, 2020-11, Vol.17 (11), p.718-731 [Tạp chí có phản biện]

COPYRIGHT 2020 Nature Publishing Group ;Springer Nature Limited 2020. ;ISSN: 1759-5002 ;EISSN: 1759-5010 ;DOI: 10.1038/s41569-020-0390-z ;PMID: 32518358

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Nhan đề:
Pregnancy and cardiovascular disease
Tác giả: Ramlakhan, Karishma P ; Johnson, Mark R ; Roos-Hesselink, Jolien W
Chủ đề: Acute Coronary Syndrome - diagnosis ; Acute Coronary Syndrome - physiopathology ; Acute Coronary Syndrome - therapy ; Adaptation (Physiology) ; Aneurysm, Dissecting - diagnosis ; Aneurysm, Dissecting - physiopathology ; Aneurysm, Dissecting - therapy ; Antihypertensive Agents - therapeutic use ; Arrhythmias, Cardiac - diagnosis ; Arrhythmias, Cardiac - physiopathology ; Arrhythmias, Cardiac - therapy ; Aspirin - therapeutic use ; Cardiac Output ; Cardiomyopathies - diagnosis ; Cardiomyopathies - physiopathology ; Cardiomyopathies - therapy ; Cardiovascular disease ; Cardiovascular diseases ; Cardiovascular Physiological Phenomena ; Cardiovascular research ; Diabetes ; Diabetes, Gestational - diagnosis ; Diabetes, Gestational - metabolism ; Diabetes, Gestational - therapy ; Disease Progression ; Endocarditis - diagnosis ; Endocarditis - physiopathology ; Endocarditis - therapy ; Female ; Fetuses ; Health aspects ; Humans ; Hypertension ; Hypertension - physiopathology ; Hypertension, Pregnancy-Induced - diagnosis ; Hypertension, Pregnancy-Induced - drug therapy ; Hypertension, Pregnancy-Induced - physiopathology ; Hypoglycemic Agents - therapeutic use ; Maternal Age ; Obesity, Maternal - metabolism ; Obesity, Maternal - physiopathology ; Physiology ; Platelet Aggregation Inhibitors - therapeutic use ; Pre-Eclampsia - physiopathology ; Pre-Eclampsia - prevention & control ; Pre-Eclampsia - therapy ; Pregnancy ; Pregnancy - metabolism ; Pregnancy - physiology ; Pregnancy Complications, Cardiovascular - diagnosis ; Pregnancy Complications, Cardiovascular - physiopathology ; Pregnancy Complications, Cardiovascular - therapy ; Pregnancy Complications, Infectious - diagnosis ; Pregnancy Complications, Infectious - physiopathology ; Pregnancy Complications, Infectious - therapy ; Pregnancy in Diabetics - metabolism ; Pregnancy, Complications of ; Risk factors ; Venous Thromboembolism - diagnosis ; Venous Thromboembolism - drug therapy ; Venous Thromboembolism - physiopathology
Là 1 phần của: Nature reviews cardiology, 2020-11, Vol.17 (11), p.718-731
Mô tả: Cardiovascular disease complicates 1-4% of pregnancies - with a higher prevalence when including hypertensive disorders - and is the leading cause of maternal death. In women with known cardiovascular pathology, such as congenital heart disease, timely counselling is possible and the outcome is fairly good. By contrast, maternal mortality is high in women with acquired heart disease that presents during pregnancy (such as acute coronary syndrome or aortic dissection). Worryingly, the prevalence of acquired cardiovascular disease during pregnancy is rising as older maternal age, obesity, diabetes mellitus and hypertension become more common in the pregnant population. Management of cardiovascular disease in pregnancy is challenging owing to the unique maternal physiology, characterized by profound changes to multiple organ systems. The presence of the fetus compounds the situation because both the cardiometabolic disease and its management might adversely affect the fetus. Equally, avoiding essential treatment because of potential fetal harm risks a poor outcome for both mother and child. In this Review, we examine how the physiological adaptations during pregnancy can provoke cardiometabolic complications or exacerbate existing cardiometabolic disease and, conversely, how cardiometabolic disease can compromise the adaptations to pregnancy and their intended purpose: the development and growth of the fetus.
Nơi xuất bản: England: Nature Publishing Group
Ngôn ngữ: English
Số nhận dạng: ISSN: 1759-5002
EISSN: 1759-5010
DOI: 10.1038/s41569-020-0390-z
PMID: 32518358
Nguồn: MEDLINE
ProQuest Central

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Pregnancy and cardiovascular disease

COPYRIGHT 2020 Nature Publishing Group ;Springer Nature Limited 2020. ;ISSN: 1759-5002 ;EISSN: 1759-5010 ;DOI: 10.1038/s41569-020-0390-z ;PMID: 32518358

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