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Adult epilepsy

The Lancet (British edition), 2023-07, Vol.402 (10399), p.412-424 [Peer Reviewed Journal]

2023 Elsevier Ltd ;Copyright © 2023 Elsevier Ltd. All rights reserved. ;2023. Elsevier Ltd ;ISSN: 0140-6736 ;EISSN: 1474-547X ;DOI: 10.1016/S0140-6736(23)01048-6 ;PMID: 37459868

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Title:
Adult epilepsy
Author: Asadi-Pooya, Ali A ; Brigo, Francesco ; Lattanzi, Simona ; Blumcke, Ingmar
Subjects: Classification ; Convulsions & seizures ; Corpus callosum ; Diet ; Disease ; DNA methylation ; Drug resistance ; Drug therapy ; EEG ; Electroencephalography ; Epidemiology ; Epigenetics ; Epilepsy ; Injuries ; Kinases ; Low income groups ; Mortality ; Neuroimaging ; Neuromodulation ; Neurosurgery ; Pathophysiology ; Patients ; Population ; Risk factors ; Seizures ; Signal transduction ; Sleep ; Surgery ; Systematic review ; Tumors ; Vagus nerve
Is Part Of: The Lancet (British edition), 2023-07, Vol.402 (10399), p.412-424
Description: Epilepsy is a common medical condition that affects people of all ages, races, social classes, and geographical regions. Diagnosis of epilepsy remains clinical, and ancillary investigations (electroencephalography, imaging, etc) are of aid to determine the type, cause, and prognosis. Antiseizure medications represent the mainstay of epilepsy treatment: they aim to suppress seizures without adverse events, but they do not affect the underlying predisposition to generate seizures. Currently available antiseizure medications are effective in around two-thirds of patients with epilepsy. Neurosurgical resection is an effective strategy to reach seizure control in selected individuals with drug-resistant focal epilepsy. Non-pharmacological treatments such as palliative surgery (eg, corpus callosotomy), neuromodulation techniques (eg, vagus nerve stimulation), and dietary interventions represent therapeutic options for patients with drug-resistant epilepsy who are not suitable for resective brain surgery.
Publisher: England: Elsevier Ltd
Language: English
Identifier: ISSN: 0140-6736
EISSN: 1474-547X
DOI: 10.1016/S0140-6736(23)01048-6
PMID: 37459868
Source: ProQuest One Psychology
AUTh Library subscriptions: ProQuest Central

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Adult epilepsy

2023 Elsevier Ltd ;Copyright © 2023 Elsevier Ltd. All rights reserved. ;2023. Elsevier Ltd ;ISSN: 0140-6736 ;EISSN: 1474-547X ;DOI: 10.1016/S0140-6736(23)01048-6 ;PMID: 37459868

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