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Review of clinical studies and recommendation for a therapeutic flow chart for diabetic macular edema

Graefe's archive for clinical and experimental ophthalmology, 2021-04, Vol.259 (4), p.815-836 [Peer Reviewed Journal]

Springer-Verlag GmbH Germany, part of Springer Nature 2020 ;Springer-Verlag GmbH Germany, part of Springer Nature 2020. ;ISSN: 0721-832X ;EISSN: 1435-702X ;DOI: 10.1007/s00417-020-04936-w ;PMID: 32997288

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Title:
Review of clinical studies and recommendation for a therapeutic flow chart for diabetic macular edema
Author: Yoshida, Shigeo ; Murakami, Tomoaki ; Nozaki, Miho ; Suzuma, Kiyoshi ; Baba, Takayuki ; Hirano, Takao ; Sawada, Osamu ; Sugimoto, Masahiko ; Takamura, Yoshihiro ; Tsuiki, Eiko
Subjects: Angiogenesis Inhibitors - therapeutic use ; Diabetes ; Diabetes Mellitus ; Diabetic Retinopathy - complications ; Diabetic Retinopathy - diagnosis ; Diabetic Retinopathy - drug therapy ; Edema ; Humans ; Intravitreal Injections ; Laser Coagulation ; Macular Edema - diagnosis ; Macular Edema - drug therapy ; Macular Edema - etiology ; Medicine ; Medicine & Public Health ; Motivation ; Ophthalmology ; Patients ; Retinopathy ; Review Article ; Vascular endothelial growth factor ; Vascular Endothelial Growth Factor A
Is Part Of: Graefe's archive for clinical and experimental ophthalmology, 2021-04, Vol.259 (4), p.815-836
Description: Diabetic macular edema (DME), characterized by exudative fluid accumulation in the macula, is the most common form of sight-threatening retinopathy in patients with diabetes. The management of DME has changed considerably in recent years, especially following the development of intravitreal anti-vascular endothelial growth factor therapy which has emerged as a first-line therapy for center-involved DME. Laser treatment, intravitreal steroid therapy, and vitrectomy are also important treatment options for DME. We believe that it is important to choose the most appropriate treatment option for DME based on the clinical evidences, in addition to the careful consideration of individual patients’ general or ocular condition, DME characteristics, patients’ motivation, and compliance to the treatment in real-world clinical practice. In this review, we have summarized important clinical evidences for the main treatments for DME, presented an expert review for these evidences, and proposed a recommended therapeutic flow chart for DME. We hope that our review of the clinical evidences and the recommended therapeutic flow chart for DME will contribute to better treatment outcome for DME.
Publisher: Berlin/Heidelberg: Springer Berlin Heidelberg
Language: English
Identifier: ISSN: 0721-832X
EISSN: 1435-702X
DOI: 10.1007/s00417-020-04936-w
PMID: 32997288
Source: AUTh Library subscriptions: ProQuest Central
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Review of clinical studies and recommendation for a therapeutic flow chart for diabetic macular edema

Springer-Verlag GmbH Germany, part of Springer Nature 2020 ;Springer-Verlag GmbH Germany, part of Springer Nature 2020. ;ISSN: 0721-832X ;EISSN: 1435-702X ;DOI: 10.1007/s00417-020-04936-w ;PMID: 32997288

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