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Risk Factors for Perioperative Morbidity in Adults Undergoing Cardiac Surgery at Children’s Hospitals

The Annals of thoracic surgery, 2022-06, Vol.113 (6), p.2062-2070 [Peer Reviewed Journal]

2022 The Society of Thoracic Surgeons ;Copyright © 2022 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. ;ISSN: 0003-4975 ;EISSN: 1552-6259 ;DOI: 10.1016/j.athoracsur.2021.04.002 ;PMID: 33864757

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  • Title:
    Risk Factors for Perioperative Morbidity in Adults Undergoing Cardiac Surgery at Children’s Hospitals
  • Author: Jain, Parag N. ; Salciccioli, Katherine B. ; Guffey, Danielle ; Byun, Jinyoung ; Cotts, Timothy B. ; Ermis, Peter ; Gaies, Michael ; Ghanayem, Nancy ; Kim, Francis ; Lasa, Javier J. ; Smith, Andrew ; Fuller, Stephanie
  • Subjects: Adult ; Cardiac Surgical Procedures - adverse effects ; Child ; Heart Defects, Congenital - etiology ; Heart Defects, Congenital - surgery ; Hospitals, Pediatric ; Humans ; Kidney Diseases - etiology ; Length of Stay ; Morbidity ; Postoperative Complications - epidemiology ; Postoperative Complications - etiology ; Retrospective Studies ; Risk Factors ; Thoracic Surgery
  • Is Part Of: The Annals of thoracic surgery, 2022-06, Vol.113 (6), p.2062-2070
  • Description: Increasing numbers of adults with congenital heart disease (ACHD) undergo cardiac surgical procedures in children’s hospitals, yet surgical outcomes data are limited. We sought to better understand the impact of preoperative risk factors on postoperative complications and cardiac intensive care unit (CICU) length of stay (LOS). Surgical CICU admissions for patients aged 18 years and older in the Pediatric Cardiac Critical Care Consortium registry from August 2014 to January 2019 in 34 hospitals were included. Primary outcomes included prolonged LOS (defined as LOS ≥90th percentile) and major complications (cardiac arrest, extracorporeal membrane oxygenation, arrhythmia requiring intervention, stroke, renal replacement therapy, infection, and reoperation/reintervention). We analyzed 1764 surgical CICU admissions. Prolonged LOS was 7 days or longer. Eighteen patients (1.0%) died, of whom 9 (0.5%) died before the LOS cutoff and were excluded from analysis. Of 1755 CICU admissions, 8.8% (n = 156) had prolonged LOS, and 23.3% (n = 413) had 1 or more major complications. Several variables, including The Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery 4/5 operation, 3 or more previous sternotomies, and preoperative renal dysfunction/dialysis were independent risk factors for both prolonged LOS and major complications (P < .05). Preoperative ventilation was associated with increased odds of prolonged LOS and preoperative arrhythmia with major complications. This analysis of postoperative ACHD care in pediatric CICUs found high complexity operations, 3 or more previous sternotomies, preoperative arrhythmias, renal dysfunction, and respiratory failure are associated with prolonged LOS and/or major complications. Future quality improvement initiatives focused on preoperative optimization and implementation of adult-specific perioperative protocols may mitigate morbidity in these patients undergoing cardiac surgical procedures at children’s hospitals.
  • Publisher: Netherlands: Elsevier Inc
  • Language: English
  • Identifier: ISSN: 0003-4975
    EISSN: 1552-6259
    DOI: 10.1016/j.athoracsur.2021.04.002
    PMID: 33864757
  • Source: MEDLINE
    Alma/SFX Local Collection
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