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The changing epidemiology of congenital heart disease

Nature reviews cardiology, 2011-01, Vol.8 (1), p.50-60 [Peer Reviewed Journal]

COPYRIGHT 2011 Nature Publishing Group ;COPYRIGHT 2011 Nature Publishing Group ;Copyright Nature Publishing Group Jan 2011 ;ISSN: 1759-5002 ;EISSN: 1759-5010 ;DOI: 10.1038/nrcardio.2010.166 ;PMID: 21045784

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Title:
The changing epidemiology of congenital heart disease
Author: Mulder, Barbara J. M ; van der Bom, Teun ; Zomer, A. Carla ; Zwinderman, Aeilko H ; Meijboom, Folkert J ; Bouma, Berto J
Subjects: Adolescent ; Adult ; Cardiac Surgical Procedures ; Child ; Child, Preschool ; Congenital heart disease ; Continuity of Patient Care ; Diagnosis ; Epidemiology ; Health aspects ; Heart Defects, Congenital - classification ; Heart Defects, Congenital - epidemiology ; Heart Defects, Congenital - etiology ; Heart Defects, Congenital - mortality ; Heart Defects, Congenital - therapy ; Humans ; Infant ; Infant, Newborn ; Pregnant women ; Prevalence ; Reoperation ; Risk Assessment ; Risk Factors ; Survival Analysis ; Survival Rate ; Terminology as Topic ; Time Factors ; Treatment Outcome ; Young Adult
Is Part Of: Nature reviews cardiology, 2011-01, Vol.8 (1), p.50-60
Description: Congenital heart disease is the most common congenital disorder in newborns. Advances in cardiovascular medicine and surgery have enabled most patients to reach adulthood. Unfortunately, prolonged survival has been achieved at a cost, as many patients suffer late complications, of which heart failure and arrhythmias are the most prominent. Accordingly, these patients need frequent follow-up by physicians with specific knowledge in the field of congenital heart disease. However, planning of care for this population is difficult, because the number of patients currently living with congenital heart disease is difficult to measure. Birth prevalence estimates vary widely according to different studies, and survival rates have not been well recorded. Consequently, the prevalence of congenital heart disease is unclear, with estimates exceeding the number of patients currently seen in cardiology clinics. New developments continue to influence the size of the population of patients with congenital heart disease. Prenatal screening has led to increased rates of termination of pregnancy. Improved management of complications has changed the time and mode of death caused by congenital heart disease. Several genetic and environmental factors have been shown to be involved in the etiology of congenital heart disease, although this knowledge has not yet led to the implementation of preventative measures. In this Review, we give an overview of the etiology, birth prevalence, current prevalence, mortality, and complications of congenital heart disease.
Publisher: England: Nature Publishing Group
Language: English
Identifier: ISSN: 1759-5002
EISSN: 1759-5010
DOI: 10.1038/nrcardio.2010.166
PMID: 21045784
Source: AUTh Library subscriptions: ProQuest Central
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The changing epidemiology of congenital heart disease

COPYRIGHT 2011 Nature Publishing Group ;COPYRIGHT 2011 Nature Publishing Group ;Copyright Nature Publishing Group Jan 2011 ;ISSN: 1759-5002 ;EISSN: 1759-5010 ;DOI: 10.1038/nrcardio.2010.166 ;PMID: 21045784

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