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Reliability of radiologists' first impression when interpreting a screening mammogram

PloS one, 2023-04, Vol.18 (4), p.e0284605-e0284605 [Peer Reviewed Journal]

Copyright: © 2023 Gandomkar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. ;COPYRIGHT 2023 Public Library of Science ;2023 Gandomkar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2023 Gandomkar et al 2023 Gandomkar et al ;2023 Gandomkar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0284605 ;PMID: 37098013

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  • Title:
    Reliability of radiologists' first impression when interpreting a screening mammogram
  • Author: Gandomkar, Ziba ; Siviengphanom, Somphone ; Suleiman, Mo'ayyad ; Wong, Dennis ; Reed, Warren ; Ekpo, Ernest U ; Xu, Dong ; Lewis, Sarah J ; Evans, Karla K ; Wolfe, Jeremy M ; Brennan, Patrick C
  • Woloschak, Gayle E.
  • Subjects: Analysis ; Breast cancer ; Experiments ; Gastrointestinal Stromal Tumors ; Humans ; Mammography ; Mammography - methods ; Medical diagnosis ; Medical screening ; Medicine and Health Sciences ; Methods ; Observer Variation ; People and Places ; Practice ; Radiologists ; Reliability analysis ; Reproducibility of Results ; Research and Analysis Methods ; Screening ; Target detection ; Visual perception
  • Is Part Of: PloS one, 2023-04, Vol.18 (4), p.e0284605-e0284605
  • Description: Previous studies showed that radiologists can detect the gist of an abnormality in a mammogram based on a half-second image presentation through global processing of screening mammograms. This study investigated the intra- and inter-observer reliability of the radiologists' initial impressions about the abnormality (or "gist signal"). It also examined if a subset of radiologists produced more reliable and accurate gist signals. Thirty-nine radiologists provided their initial impressions on two separate occasions, viewing each mammogram for half a second each time. The intra-class correlation (ICC) values showed poor to moderate intra-reader reliability. Only 13 radiologists had an ICC of 0.6 or above, which is considered the minimum standard for reliability, and only three radiologists had an ICC exceeding 0.7. The median value for the weighted Cohen's Kappa was 0.478 (interquartile range = 0.419-0.555). The Mann-Whitney U-test showed that the "Gist Experts", defined as those who outperformed others, had significantly higher ICC values (p = 0.002) and weighted Cohen's Kappa scores (p = 0.026). However, even for these experts, the intra-radiologist agreements were not strong, as an ICC of at least 0.75 indicates good reliability and the signal from none of the readers reached this level of reliability as determined by ICC values. The inter-reader reliability of the gist signal was poor, with an ICC score of 0.31 (CI = 0.26-0.37). The Fleiss Kappa score of 0.106 (CI = 0.105-0.106), indicating only slight inter-reader agreement, confirms the findings from the ICC analysis. The intra- and inter-reader reliability analysis showed that the radiologists' initial impressions are not reliable signals. In particular, the absence of an abnormal gist does not reliably signal a normal case, so radiologists should keep searching. This highlights the importance of "discovery scanning," or coarse screening to detect potential targets before ending the visual search.
  • Publisher: United States: Public Library of Science
  • Language: English
  • Identifier: ISSN: 1932-6203
    EISSN: 1932-6203
    DOI: 10.1371/journal.pone.0284605
    PMID: 37098013
  • Source: Public Library of Science (PLoS) Journals Open Access
    PubMed (Medline)
    Geneva Foundation Free Medical Journals at publisher websites
    AUTh Library subscriptions: ProQuest Central
    MEDLINE
    DOAJ Directory of Open Access Journals

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