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Iridoid glycosides isolated from Oldenlandia diffusa inhibit LDL-oxidation

Archives of Pharmacal Research, 2005, 28(10), , pp.1156-1160 [Peer Reviewed Journal]

ISSN: 0253-6269 ;EISSN: 1976-3786 ;DOI: 10.1007/BF02972979 ;PMID: 16276972

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Title:
Iridoid glycosides isolated from Oldenlandia diffusa inhibit LDL-oxidation
Author: Kim, Dong-Hyun ; Lee, Hyo-Jung ; Oh, Young-Jun ; Kim, Min-Jung ; Kim, Sung-Hoon ; Jeong, Tae-Sook ; Baek, Nam-In
Subjects: Glucosides - chemistry ; Glucosides - isolation & purification ; Glucosides - pharmacology ; Glycosides - chemistry ; Glycosides - isolation & purification ; Glycosides - pharmacology ; Humans ; Iridoid Glucosides ; Iridoids - chemistry ; Iridoids - isolation & purification ; Iridoids - pharmacology ; Lipoproteins, LDL - metabolism ; Molecular Structure ; Oldenlandia - chemistry ; Oxidation-Reduction - drug effects ; Plant Extracts - chemistry ; Plant Extracts - isolation & purification ; Plant Extracts - pharmacology ; Structure-Activity Relationship ; 약학
Is Part Of: Archives of Pharmacal Research, 2005, 28(10), , pp.1156-1160
Description: An iridoid glycoside, oldenlandoside III (5) was isolated from the n-butanol fraction of methanol extracts of the aerial parts of Oldenlandia diffusa Roxb. along with six others previously characterized iridoid glycosides; geniposidic acid (1), scandoside (2), feretoside (3), 10-omicron-benzoylscandoside methyl ester (4), asperulosidic acid (6) and deacetylasperulosidic acid (7). Compounds 1, 2, and 7 inhibited LDL-oxidation, and showed 63.3+/-2.0, 62.2+/-1.6, and 63.8+/-1.5% inhibition, respectively, at a concentration of 20 microg/mL.
Publisher: Korea (South): 대한약학회
Language: English;Korean
Identifier: ISSN: 0253-6269
EISSN: 1976-3786
DOI: 10.1007/BF02972979
PMID: 16276972
Source: MEDLINE
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Iridoid glycosides isolated from Oldenlandia diffusa inhibit LDL-oxidation

ISSN: 0253-6269 ;EISSN: 1976-3786 ;DOI: 10.1007/BF02972979 ;PMID: 16276972

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