skip to main content
Guest
My Research
My Account
Sign out
Sign in
This feature requires javascript
Library Search
Find Databases
Browse Search
E-Journals A-Z
E-Books A-Z
Citation Linker
Help
Language:
English
Vietnamese
This feature required javascript
This feature requires javascript
Primo Search
All Library Resources
All
Course Materials
Course Materials
Search For:
Clear Search Box
Search in:
All Library Resources
Or hit Enter to replace search target
Or select another collection:
Search in:
All Library Resources
Search in:
Print Resources
Search in:
Digital Resources
Search in:
Online E-Resources
Advanced Search
Browse Search
This feature requires javascript
Search Limited to:
Search Limited to:
Resource type
criteria input
All items
Books
Articles
Images
Audio Visual
Maps
Graduate theses
Show Results with:
criteria input
that contain my query words
with my exact phrase
starts with
Show Results with:
Search type Index
criteria input
anywhere in the record
in the title
as author/creator
in subject
Full Text
ISBN
ISSN
TOC
Keyword
Field
Show Results with:
in the title
Show Results with:
anywhere in the record
in the title
as author/creator
in subject
Full Text
ISBN
ISSN
TOC
Keyword
Field
This feature requires javascript
The association between serum and urinary cotinine levels and arterial stiffness in the birth-to-twenty and African-predict cohort studies
Digital Resources/Online E-Resources
Citations
Cited by
View Online
Details
Recommendations
Reviews
Times Cited
External Links
This feature requires javascript
Actions
Add to My Research
Remove from My Research
E-mail
Print
Permalink
Citation
EasyBib
EndNote
RefWorks
Delicious
Export RIS
Export BibTeX
This feature requires javascript
Title:
The association between serum and urinary cotinine levels and arterial stiffness in the birth-to-twenty and African-predict cohort studies
Author:
Nembulu, Betty
Subjects:
Cardiovascular disease
;
Serum
;
Urinary cotinine
Description:
A research report submitted in partial fulfilment of the requirement for the degree of Master of Science in Medicine to the Faculty of Health Sciences, University of the Witwatersrand, School of Clinical Medicine, Johannesburg, 2023 Cardiovascular disease (CVD) is the leading cause of mortality globally, resulting from various risk factors, including genes, environment, demographics and poor lifestyle behaviours, such as tobacco exposure, a preventable CVD risk factor. Arterial stiffness is a predictor of CVD, pulse wave velocity (PWV) is often used to stratify the risk for development of CVD. The aim of this study was to examine the relationship between tobacco exposure (own use and environmental tobacco smoke [ETS]), as assessed by the biomarker cotinine, and arterial stiffness in South African adults and children of African ancestry. Two South African cohort studies of young adults, the African-PREDICT study (n=587 African adult men and women, 20-30 years) and Birth-to-Twenty-Plus study (n=95 African adult women, 28-68 years and n=47 African children, 4-10 years), were explored. Chemiluminescence method on the IMMULITE system was used to measure cotinine (serum and urinary). Cotinine values above 10 ng/ml were considered for tobacco exposed and PWV was measured using the SphygmoCor XCEL device. Thirty one percent adults and forty five percent children were classified as tobacco exposed. Linear regression showed that, in both children and adults, tobacco exposure was associated with arterial stiffness in the univariate analysis but not in multivariate analysis. Blood pressure (BP) was higher in tobacco exposed individuals (adults and children) compared to the non-exposed counterparts. These findings highlight the need to stop tobacco use to maintain ideal cardiovascular (CV) health. Highlighting the need for a thorough assessment of the current guidelines on tobacco cessation strategies in South Africa. Wellcome Trust Non-Communicable Disease Research Unit (NCDR) Centre of Excellence in Human Development South African Medical Research Council (SAMRC) TL (2024)
Creation Date:
2024
Language:
English
Source:
WIReDSpace
This feature requires javascript
This feature requires javascript
Back to results list
This feature requires javascript
This feature requires javascript
Searching Remote Databases, Please Wait
Searching for
in
scope:(TDTS),scope:(SFX),scope:(TDT),scope:(SEN),primo_central_multiple_fe
Show me what you have so far
This feature requires javascript
This feature requires javascript