Language:

Obesity and risk of colorectal cancer: a systematic review of prospective studies

PloS one, 2013-01, Vol.8 (1), p.e53916-e53916 [Peer Reviewed Journal]

COPYRIGHT 2013 Public Library of Science ;COPYRIGHT 2013 Public Library of Science ;2013 Ma et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2013 Ma et al 2013 Ma et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0053916 ;PMID: 23349764

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Obesity and risk of colorectal cancer: a systematic review of prospective studies
Author: Ma, Yanlei ; Yang, Yongzhi ; Wang, Feng ; Zhang, Peng ; Shi, Chenzhang ; Zou, Yang ; Qin, Huanlong
Gorlova, Olga Y.
Subjects: Body mass ; Body Mass Index ; Body size ; Cancer ; Cancer research ; Colon ; Colon cancer ; Colorectal cancer ; Colorectal carcinoma ; Colorectal Neoplasms - complications ; Confidence intervals ; Exercise ; Health aspects ; Health risk assessment ; Health risks ; Humans ; Insulin-like growth factors ; Lists ; Medicine ; Obesity ; Obesity - complications ; Oncology, Experimental ; Prospective Studies ; Rectum ; Reviews ; Risk ; Risk Assessment ; Risk Factors ; Systematic review ; Waist Circumference
Is Part Of: PloS one, 2013-01, Vol.8 (1), p.e53916-e53916
Description: Mounting evidence indicates that obesity may be associated with the risk of colorectal cancer (CRC). To conduct a systematic review of prospective studies assessing the association of obesity with the risk of CRC using meta-analysis. Relevant studies were identified by a search of MEDLINE and EMBASE databases before January 2012, with no restrictions. We also reviewed reference lists from retrieved articles. We included prospective studies that reported relative risk (RR) estimates with 95% confidence intervals (CIs) for the association between general obesity [measured using body mass index (BMI)] or central obesity [measured using waist circumference (WC)] and the risk of colorectal, colon, or rectal cancer. Approximately 9, 000, 000 participants from several countries were included in this analysis. 41 studies on general obesity and 13 studies on central obesity were included in the meta-analysis. The pooled RRs of CRC for the obese vs. normal category of BMI were 1.334 (95% CI, 1.253-1.420), and the highest vs. lowest category of WC were 1.455 (95% CI, 1.327-1.596). There was heterogeneity among studies of BMI (P<0.001) but not among studies of WC (P=0.323). Both of general and central obesity were positively associated with the risk of CRC in this meta-analysis.
Publisher: United States: Public Library of Science
Language: English
Identifier: ISSN: 1932-6203
EISSN: 1932-6203
DOI: 10.1371/journal.pone.0053916
PMID: 23349764
Source: Public Library of Science (PLoS) Journals Open Access
Geneva Foundation Free Medical Journals at publisher websites
MEDLINE
Directory of Open Access Journals
PubMed Central（OA）
ProQuest Central

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Obesity and risk of colorectal cancer: a systematic review of prospective studies

Searching Remote Databases, Please Wait