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Small RNAs in Bacteria and Archaea: Who They Are, What They Do, and How They Do It

Advances in Genetics, 2015, p.133 [Peer Reviewed Journal]

ISBN: 9780128036945 ;ISBN: 012803694X ;ISBN: 9780128036952 ;ISBN: 0128036958 ;EISBN: 9780128036952 ;EISBN: 0128036958 ;DOI: 10.1016/bs.adgen.2015.05.001 ;OCLC: 929142307 ;LCCallNum: QH430 .F384 2015

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  • Title:
    Small RNAs in Bacteria and Archaea: Who They Are, What They Do, and How They Do It
  • Author: Friedmann, Theodore ; Dunlap, Jay C ; Goodwin, Stephen F
  • Subjects: Cellular biology ; Genetics (non-medical)
  • Is Part Of: Advances in Genetics, 2015, p.133
  • Description: Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs, thereby globally affecting essentially any conceivable traitestress responses, adaptive metabolic changes, virulence etc. The sRNAs display many distinct mechanisms of action, most of them through effects on target mRNA translation and/or stability, and helper proteins like Hfq often play key roles. Recent data highlight the interplay between posttranscriptional control by sRNAs and transcription factor-mediated transcriptional control, and cross talk through mutual regulation of regulators. Based on the properties that distinguish sRNA-type from transcription factors-type control, we begin to glimpse why sRNAs have evolved as a second, essential layer of gene regulation. This review will discuss the prevalence of sRNAs, who they are, what biological roles they play, and how they carry out their functions.
  • Publisher: United States: Elsevier Science & Technology
  • Language: English
  • Identifier: ISBN: 9780128036945
    ISBN: 012803694X
    ISBN: 9780128036952
    ISBN: 0128036958
    EISBN: 9780128036952
    EISBN: 0128036958
    DOI: 10.1016/bs.adgen.2015.05.001
    OCLC: 929142307
    LCCallNum: QH430 .F384 2015
  • Source: ScholarVox International
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