Language:

Perihematomal Edema After Intracerebral Hemorrhage: An Update on Pathogenesis, Risk Factors, and Therapeutic Advances

Frontiers in immunology, 2021-10, Vol.12, p.740632-740632 [Peer Reviewed Journal]

Copyright © 2021 Chen, Chen, Chang, Wei, Feng and Wang. ;Copyright © 2021 Chen, Chen, Chang, Wei, Feng and Wang 2021 Chen, Chen, Chang, Wei, Feng and Wang ;ISSN: 1664-3224 ;EISSN: 1664-3224 ;DOI: 10.3389/fimmu.2021.740632 ;PMID: 34737745

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Perihematomal Edema After Intracerebral Hemorrhage: An Update on Pathogenesis, Risk Factors, and Therapeutic Advances
Author: Chen, Yihao ; Chen, Shengpan ; Chang, Jianbo ; Wei, Junji ; Feng, Ming ; Wang, Renzhi
Subjects: Brain - diagnostic imaging ; Brain - pathology ; Brain Edema - etiology ; Brain Edema - physiopathology ; Brain Edema - prevention & control ; Cerebral Hemorrhage - complications ; Cerebral Hemorrhage - physiopathology ; Cerebral Hemorrhage - therapy ; Glyburide - therapeutic use ; Hematoma - etiology ; Hematoma - physiopathology ; Hematoma - prevention & control ; Humans ; Hypoglycemic Agents - therapeutic use ; Immunology ; intracerebral hemorrhage ; Magnetic Resonance Imaging ; Neurogenic Inflammation ; neuroinflammation ; pathophysiology ; perihematomal edema ; Risk Factors ; therapies
Is Part Of: Frontiers in immunology, 2021-10, Vol.12, p.740632-740632
Description: Intracerebral hemorrhage (ICH) has one of the worst prognoses among patients with stroke. Surgical measures have been adopted to relieve the mass effect of the hematoma, and developing targeted therapy against secondary brain injury (SBI) after ICH is equally essential. Numerous preclinical and clinical studies have demonstrated that perihematomal edema (PHE) is a quantifiable marker of SBI after ICH and is associated with a poor prognosis. Thus, PHE has been considered a promising therapeutic target for ICH. However, the findings derived from existing studies on PHE are disparate and unclear. Therefore, it is necessary to classify, compare, and summarize the existing studies on PHE. In this review, we describe the growth characteristics and relevant underlying mechanism of PHE, analyze the contributions of different risk factors to PHE, present the potential impact of PHE on patient outcomes, and discuss the currently available therapeutic strategies.
Publisher: Switzerland: Frontiers Media S.A
Language: English
Identifier: ISSN: 1664-3224
EISSN: 1664-3224
DOI: 10.3389/fimmu.2021.740632
PMID: 34737745
Source: PubMed Central (Open access)
Geneva Foundation Free Medical Journals at publisher websites
MEDLINE
ROAD: Directory of Open Access Scholarly Resources
DOAJ Directory of Open Access Journals

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Perihematomal Edema After Intracerebral Hemorrhage: An Update on Pathogenesis, Risk Factors, and Therapeutic Advances

Copyright © 2021 Chen, Chen, Chang, Wei, Feng and Wang. ;Copyright © 2021 Chen, Chen, Chang, Wei, Feng and Wang 2021 Chen, Chen, Chang, Wei, Feng and Wang ;ISSN: 1664-3224 ;EISSN: 1664-3224 ;DOI: 10.3389/fimmu.2021.740632 ;PMID: 34737745

Searching Remote Databases, Please Wait