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심혈관 질환과 리보플라빈 및 나이아신과의 상관성 연구
Korean journal of clinical laboratory science, 2019-12, Vol.51 (4), p.484-494
[Peer Reviewed Journal]
ISSN: 1738-3544 ;EISSN: 2288-1662
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Title:
심혈관 질환과 리보플라빈 및 나이아신과의 상관성 연구
Author:
안지영
;
김인식
;
이지숙
;
Ahn, Ji Yeong
;
Kim, In Sik
;
Lee, Ji-Sook
Is Part Of:
Korean journal of clinical laboratory science, 2019-12, Vol.51 (4), p.484-494
Description:
Cardiovascular disease is caused by different factors. These factors include innateness factors such as aging, biological factors such as high blood pressure, and environmental factors such as stress. This study examined the factors associated with cardiovascular disease and the ways to reduce its prevalence by analyzing the data within the Korean National Health and Nutrition Examination Reports from 2013 to 2017, and particularly the survey and examination data for people over 50 years old. The study population was divided into two groups: members of the first group consumed riboflavin and niacin at the recommended rate while those in the second group did not. Riboflavin intake was correlated with hypertension, hyperglycemia, and a low HDL-cholesterol level, whereas niacin intake was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level. The combination of niacin and riboflavin intakes was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level (P<0.05). The combined intake of the recommended levels of riboflavin and niacin reduced the average physiological factor abnormality rate to 80%. Taken together, the beneficial effects of riboflavin and niacin can reduce the prevalence of cardiovascular disease. 심혈관 질환의 위험 요인은 선천적으로 노화, 당 대사의 문제, 가족력과 성별이 있으며 생리학적 요인으로 고혈압, 혈청 콜레스테롤이 있다. 그 외 환경적 요인으로 흡연, 섭식, 스트레스 등이 있다. 본 연구는 최근 2013~2017년 국민건강영양조사 내용을 바탕으로 50세이상 남녀를 대상으로 한 건강설문조사와 검진조사를 이용하여 심혈관 질환의 위험 요인 및 유병률을 낮출 수 있는 방법을 연구하고자 하였다. 생리학적 요소와 영양성분 권장섭취 여부와의 상관성을 보기 위해 리보플라빈과 나이아신의 권장량을 확인하여 권장섭취군과 비권장섭취군으로 나눈 후 생리학적 요소변수와 분석하였다. 리보플라빈은 고혈압, 고혈당, 낮은 HDL-콜레스테롤에서, 나이아신은 고혈압, 고혈당, 허리둘레, 낮은 HDL-콜레스테롤에서, 둘을 복합적으로 보았을 때는 고혈압, 고혈당, 허리 둘레, 낮은 HDL-콜레스테롤에서 상관성이 있는 것으로 나타났다 (P<0.05). 결론적으로 리보플라빈, 나이아신의 권장섭취는 고혈당, 허리 둘레, HDL-콜레스테롤 등의 생리학적 요소에 영향을 줄 수 있으며, 이를 통해 심혈관 질환의 유병률을 낮출 수 있다. 이는 심혈관 질환의 위험율을 낮출 수 있는 가치 있는 연구로서 의의가 있다고 사료된다.
Language:
Korean
Identifier:
ISSN: 1738-3544
EISSN: 2288-1662
Source:
Directory of Open Access Journals
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