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Aspects of Point-of-Care Diagnostics for Personalized Health Wellness

International journal of nanomedicine, 2021-01, Vol.16, p.383-402 [Peer Reviewed Journal]

2021 Kumar et al. ;COPYRIGHT 2021 Dove Medical Press Limited ;2021. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 Kumar et al. 2021 Kumar et al. ;ISSN: 1178-2013 ;ISSN: 1176-9114 ;EISSN: 1178-2013 ;DOI: 10.2147/IJN.S267212 ;PMID: 33488077

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Title:
Aspects of Point-of-Care Diagnostics for Personalized Health Wellness
Author: Kumar, Sandeep ; Nehra, Monika ; Khurana, Sakina ; Dilbaghi, Neeraj ; Kumar, Vanish ; Kaushik, Ajeet ; Kim, Ki-Hyun
Subjects: Automation ; Biomarkers ; Care and treatment ; Communicable diseases ; Communicable Diseases - diagnosis ; Developing countries ; FDA approval ; Glucose monitoring ; Health aspects ; HIV ; Homeopathy ; Human immunodeficiency virus ; Humans ; Immunoassay ; Infectious diseases ; Lab-On-A-Chip Devices ; Laboratories ; lateral flow strips ; LDCs ; Materia medica and therapeutics ; Microfluidics ; Mortality ; Nanomaterials ; Pathogens ; Patients ; point of care devices ; Point of care testing ; Precision Medicine - methods ; Review ; Signal transduction ; Smartphone ; Smartphones ; Surface chemistry ; Syphilis ; Therapeutics ; Tropical diseases ; Urine
Is Part Of: International journal of nanomedicine, 2021-01, Vol.16, p.383-402
Description: Advancements in analytical diagnostic systems for point-of-care (POC) application have gained considerable attention because of their rapid operation at the site required to manage severe diseases, even in a personalized manner. The POC diagnostic devices offer easy operation, fast analytical outcome, and affordable cost, which promote their advanced research and versatile adoptability. Keeping advantages in view, considerable efforts are being made to design and develop smart sensing components such as miniaturized transduction, interdigitated electrodes-based sensing chips, selective detection at low level, portable packaging, and sustainable durability to promote POC diagnostics according to the needs of patient care. Such effective diagnostics systems are in demand, which creates the challenge to make them more efficient in every aspect to generate a desired bio-informatic needed for better health access and management. Keeping advantages and scope in view, this mini review focuses on practical scenarios associated with miniaturized analytical diagnostic devices at POC application for targeted disease diagnostics smartly and efficiently. Moreover, advancements in technologies, such as smartphone-based operation, paper-based sensing assays, and lab-on-a-chip (LOC) which made POC more sensitive, informative, and suitable for major infectious disease diagnosis, are the main focus here. Besides, POC diagnostics based on automated patient sample integration with a sensing platform is continuously improving therapeutics interventions against specific infectious disease. This review also discussed challenges associated with state-of-the-art technology along with future research opportunities to design and develop next generation POC diagnostic systems needed to manage infectious diseases in a personalized manner.
Publisher: New Zealand: Dove Medical Press Limited
Language: English
Identifier: ISSN: 1178-2013
ISSN: 1176-9114
EISSN: 1178-2013
DOI: 10.2147/IJN.S267212
PMID: 33488077
Source: GFMER Free Medical Journals
MEDLINE
PubMed Central
DOVE Medical Press Journals
Coronavirus Research Database
ProQuest Central
DOAJ Directory of Open Access Journals

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Aspects of Point-of-Care Diagnostics for Personalized Health Wellness

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