Language:

Association between schizophrenia and an autoimmune bullous skin disease-pemphigus: a population-based large-scale study

Epidemiology and psychiatric sciences, 2019-04, Vol.28 (2), p.191-198 [Peer Reviewed Journal]

Copyright © Cambridge University Press 2017 ;Cambridge University Press 2017 2017 Cambridge University Press ;ISSN: 2045-7960 ;EISSN: 2045-7979 ;DOI: 10.1017/S204579601700052X ;PMID: 28942756

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Association between schizophrenia and an autoimmune bullous skin disease-pemphigus: a population-based large-scale study
Author: Kridin, K. ; Zelber-Sagi, S. ; Comaneshter, D. ; Cohen, A. D.
Subjects: Adolescent ; Adult ; Age ; Aged ; Autoimmune Diseases ; Child ; Chronic illnesses ; Comorbidity ; Cross-Sectional Studies ; Databases, Factual ; Ethics ; Ethnicity ; Female ; Females ; Health services ; Hospitals ; Humans ; Immunology ; Israel - epidemiology ; Medical personnel ; Mental disorders ; Middle Aged ; Minority & ethnic groups ; Mortality ; Multivariate analysis ; Original ; Original Articles ; Pathogenesis ; Patients ; Pemphigus ; Pemphigus - epidemiology ; Physicians ; Population ; Population studies ; Population Surveillance ; Prevalence ; Primary care ; Regression models ; Retrospective Studies ; Schizophrenia ; Schizophrenia - epidemiology ; Schizophrenic Psychology ; Skin diseases ; Statistical analysis ; Studies ; Young Adult
Is Part Of: Epidemiology and psychiatric sciences, 2019-04, Vol.28 (2), p.191-198
Description: Immunological hypotheses have become increasingly prominent suggesting that autoimmunity may be involved in the pathogenesis of schizophrenia. Schizophrenia was found to be associated with a wide range of autoimmune diseases. However, the association between pemphigus and schizophrenia has not been established yet. We aimed to estimate the association between pemphigus and schizophrenia using a large-scale real-life computerised database. This study was conducted as a cross-sectional study utilising the database of Clalit Health Services. The proportion of schizophrenia was compared between patients diagnosed with pemphigus and age-, gender- and ethnicity-matched control subjects. Univariate analysis was performed using χ2 and Student's t-test and a multivariate analysis was performed using a logistic regression model. A total of 1985 pemphigus patients and 9874 controls were included in the study. The prevalence of schizophrenia was greater in patients with pemphigus as compared to the control group (2.0% v. 1.3%, respectively; p = 0.019). In a multivariate analysis, pemphigus was significantly associated with schizophrenia (OR, 1.5; 95% CI, 1.1-2.2). The association was more prominent among females, patients older than 60 years, and Jews. Pemphigus is significantly associated with schizophrenia. Physicians treating patients with pemphigus should be aware of this possible association. Patients with pemphigus should be carefully assessed for comorbid schizophrenia and be treated appropriately.
Publisher: Cambridge, UK: Cambridge University Press
Language: English;Italian
Identifier: ISSN: 2045-7960
EISSN: 2045-7979
DOI: 10.1017/S204579601700052X
PMID: 28942756
Source: ProQuest One Psychology
Journals@Ovid Open Access Journal Collection Rolling
MEDLINE
PubMed Central
ProQuest Central

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Association between schizophrenia and an autoimmune bullous skin disease-pemphigus: a population-based large-scale study

Copyright © Cambridge University Press 2017 ;Cambridge University Press 2017 2017 Cambridge University Press ;ISSN: 2045-7960 ;EISSN: 2045-7979 ;DOI: 10.1017/S204579601700052X ;PMID: 28942756

Searching Remote Databases, Please Wait