Language:

Contrast-Induced Encephalopathy After Endovascular Thrombectomy for Acute Ischemic Stroke

Stroke (1970), 2020-12, Vol.51 (12), p.3756-3759 [Peer Reviewed Journal]

2020 American Heart Association, Inc. ;ISSN: 0039-2499 ;EISSN: 1524-4628 ;DOI: 10.1161/STROKEAHA.120.031518 ;PMID: 33121385

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Contrast-Induced Encephalopathy After Endovascular Thrombectomy for Acute Ischemic Stroke
Author: Chu, Yung-Tsai ; Lee, Kang-Po ; Chen, Chih-Hao ; Sung, Pi-Shan ; Lin, Yen-Heng ; Lee, Chung-Wei ; Tsai, Li-Kai ; Tang, Sung-Chun ; Jeng, Jiann-Shing
Subjects: Acute Kidney Injury - chemically induced ; Acute Kidney Injury - epidemiology ; Aged ; Aged, 80 and over ; Brain Diseases - chemically induced ; Brain Diseases - diagnostic imaging ; Brain Diseases - epidemiology ; Brain Diseases - physiopathology ; Brain Edema - chemically induced ; Brain Edema - diagnostic imaging ; Brain Edema - physiopathology ; Contrast Media - administration & dosage ; Contrast Media - adverse effects ; Endovascular Procedures ; Female ; Humans ; Incidence ; Ischemic Stroke - physiopathology ; Ischemic Stroke - surgery ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Postoperative Complications - chemically induced ; Postoperative Complications - diagnostic imaging ; Postoperative Complications - epidemiology ; Postoperative Complications - physiopathology ; Thrombectomy ; Tomography, X-Ray Computed
Is Part Of: Stroke (1970), 2020-12, Vol.51 (12), p.3756-3759
Description: BACKGROUND AND PURPOSE:Contrast-induced encephalopathy (CIE) is a rare and underrecognized complication after endovascular thrombectomy (EVT) for acute ischemic stroke. This study investigated the incidence and risk factors of CIE in patients who underwent EVT. METHODS:Consecutive patients with acute ischemic stroke who received EVT between September 2014 and December 2019 at 2 medical centers were included. CIE was diagnosed on clinical criteria of neurological deterioration or delayed improvement within 24 hours after the procedure that was unexplained by the infarct or hemorrhagic transformation and radiological criterion of edematous change extending beyond the infarct core accompanied by contrast staining. RESULTS:Of 421 patients with acute ischemic stroke who received EVT, 7 (1.7%) developed CIE. The manifestations included worsening of focal neurological signs, coma, and seizure. Patients with CIE were more likely to experience contrast-induced acute kidney injury than were those without CIE, but the volume of contrast medium was comparable between the two groups. The independent risk factors for CIE included renal dysfunction (defined as an estimated glomerular filtration rate <45 mL/min per 1.73 m; odds ratio, 5.77 [95% CI, 1.37–24.3]; P=0.02) and history of stroke (odds ratio, 4.96 [95% CI, 1.15–21.3]; P=0.03). Patients with CIE were less likely to achieve favorable functional outcomes (odds ratio, 0.09 [95% CI, 0.01–0.87]; P=0.04). CONCLUSIONS:CIE should be suspected in patients with clinical worsening after EVT accompanied by imaging evidence of contrast staining and edematous changes, especially in patients with renal dysfunction or history of stroke.
Publisher: United States: American Heart Association, Inc
Language: English
Identifier: ISSN: 0039-2499
EISSN: 1524-4628
DOI: 10.1161/STROKEAHA.120.031518
PMID: 33121385
Source: MEDLINE
Alma/SFX Local Collection

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Contrast-Induced Encephalopathy After Endovascular Thrombectomy for Acute Ischemic Stroke

2020 American Heart Association, Inc. ;ISSN: 0039-2499 ;EISSN: 1524-4628 ;DOI: 10.1161/STROKEAHA.120.031518 ;PMID: 33121385

Searching Remote Databases, Please Wait