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Final Analysis of a Trial of M72/AS01(sub E) Vaccine to Prevent Tuberculosis
The New England journal of medicine, 2019-12, Vol.381 (25), p.2429
[Peer Reviewed Journal]
ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa1909953
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Title:
Final Analysis of a Trial of M72/AS01(sub E) Vaccine to Prevent Tuberculosis
Author:
Lempicki, Maria
;
Pascal, Thierry G
;
Evans, Thomas G
;
Gillard, Paul
;
Thienemann, Friedrich
;
Nduba, Videlis
;
Ayles, Helen M
;
Salaun, Bruno
;
Hellstrom, Elizabeth
;
Scriba, Thomas J
;
Van Der Meeren, Olivier
;
Akite, Elaine J
;
Van Brakel, Elana
;
Roman, Francois
;
Malahleha, Mookho
;
Bollaerts, Anne
;
Tameris, Michele
;
Hatherill, Mark
;
Ginsberg, Ann M
;
Demoitie, Marie-Ange
;
Wilkinson, Robert J
;
Martinson, Neil
;
Mesia Vela, Doris
;
Muyoyeta, Monde
;
Innes, James C
;
Tait, Dereck R
;
Diacon, Andreas
Subjects:
Control
;
Mycobacterium tuberculosis
;
Testing
;
Treatment outcome
;
Tuberculosis vaccines
Is Part Of:
The New England journal of medicine, 2019-12, Vol.381 (25), p.2429
Description:
The efficacy of the M72/AS01(sub E) vaccine tuberculosis to prevent tuberculosis was 49.7% at month 36. An according-to-protocol efficacy cohort has 3,289 participants. There were 13 of the 1626 participants in the vaccine group, compared with 26 of the 1663 participants in the placebo group, that had first-case-definition cases of tuberculosis (0.3 vs. 0.6 cases per 100 person-years).
Publisher:
Massachusetts Medical Society
Language:
English
Identifier:
ISSN: 0028-4793
EISSN: 1533-4406
DOI: 10.1056/NEJMoa1909953
Source:
ProQuest One Psychology
ProQuest Central
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