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Varicella Zoster Virus Pneumonia without Signs of Vesicular Skin and Mucosa Lesions During Pregnancy

Flora (Ankara, Turkey), 2023-09, Vol.28 (3), p.562-568 [Peer Reviewed Journal]

ISSN: 1300-932X ;DOI: 10.5578/flora.20239728

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  • Title:
    Varicella Zoster Virus Pneumonia without Signs of Vesicular Skin and Mucosa Lesions During Pregnancy
  • Author: Yaqoobi, Hasibullah ; Bal, Tayibe
  • Subjects: chickenpox infection ; pregnancy ; varicella pneumonia ; varicella zoster virus
  • Is Part Of: Flora (Ankara, Turkey), 2023-09, Vol.28 (3), p.562-568
  • Description: Chickenpox is an infectious disease caused by the varicella zoster virus (VZV). VZV causes two different clinical pictures, chickenpox and shingles. Chickenpox is a preventable, benign disease with a vesicular rash, but it can cause life-threatening organ involvement such as pneumonia. Pneumonia is more common and dangerous in pregnant women. The importance of history and clinical findings in diagnosis is indisputable. Isolation of VZV from vesicular fluid is the gold standard in laboratory diagnosis. From body fluids, detection of VZV nucleic acid by Polymerase Chain Reaction (PCR) and antigen by Direct Immunofluorescent antibody (DFA) is sensitive and specific. Detection of IgM and IgG by serological methods such as Enzyme-Linked Immunosorbet Assay (ELİSA), Enzyme Linked Florencent assay (ELFA) is used for diagnosis. In severe and atypical cases, RT-PCR is the appropriate method to rapid demonstration of VZV. Demonstrating VZV IgM and IgG positivity with serological methods such as ELISA and ELFA is also important for the diagnosis of acute chickenpox. Reducing complications, antiviral treatment and supportive treatment are the cornerstones of chickenpox management. Here, we wanted to share a pregnant case who had not had chickenpox/shingles before, had no history of contact with chickenpox, had not been vaccinated against chickenpox, and developed pneumonia due to varicella without skin and mucous membrane involvement.
  • Publisher: Bilimsel Tip Yayinevi
  • Language: English
  • Identifier: ISSN: 1300-932X
    DOI: 10.5578/flora.20239728
  • Source: DOAJ Directory of Open Access Journals
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