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Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by 18F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case

World journal of nuclear medicine, 2021-10, Vol.20 (4), p.379-381 [Peer Reviewed Journal]

Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ;COPYRIGHT 2021 Medknow Publications and Media Pvt. Ltd. ;2021. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Copyright: © 2021 World Journal of Nuclear Medicine 2021 ;ISSN: 1450-1147 ;EISSN: 1607-3312 ;DOI: 10.4103/wjnm.wjnm_74_21 ;PMID: 35018155

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  • Title:
    Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by 18F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and aggressive case
  • Author: Purkayastha, Abhishek ; Suhag, Virender ; Taneja, Sachin ; Husain, Azhar
  • Subjects: Bones ; Cancer ; Carcinoma ; Case Report ; Developing countries ; Development and progression ; LDCs ; Literature reviews ; Metastasis ; Muscles ; Penis ; PET imaging ; Positron emission ; Radiation therapy ; Tomography
  • Is Part Of: World journal of nuclear medicine, 2021-10, Vol.20 (4), p.379-381
  • Description: Abstract Carcinoma penis is a rare malignancy accounting 0.5%–1% of cases in the developed countries with a slightly higher incidence in the developing nations. Slow locoregional progression is characteristic of penile carcinoma (PC) and distant metastases are very uncommon. We hereby report a case of highly aggressive squamous cell PC in a 46-year-old male with fulminant upfront distant dissemination to left supraclavicular lymph nodes (LNs) without involving the inguinal and pelvic nodes detected by whole-body 18 F-fluorodeoxyglucose positron-emission tomography scan. The scan also detected lytic destructive lesion involving the pelvic and adjacent bones with infiltration of skeletal muscles. He was treated with palliative radiotherapy to the wight-bearing sites followed by systemic chemotherapy. A thorough review of literature reveals that our case may be one of the rarest cases ever reported in world literature where an asymptomatic PC presents with upfront supraclavicular LN metastasis bypassing the inguinal, pelvic, and retroperitoneal LN chains.
  • Publisher: A-12, 2nd Floor, Sector 2, Noida-201301 UP, India: Thieme Medical and Scientific Publishers Pvt. Ltd
  • Language: English
  • Identifier: ISSN: 1450-1147
    EISSN: 1607-3312
    DOI: 10.4103/wjnm.wjnm_74_21
    PMID: 35018155
  • Source: PubMed Central (Open access)
    Geneva Foundation Free Medical Journals at publisher websites
    AUTh Library subscriptions: ProQuest Central
    Alma/SFX Local Collection
    Thieme (Open access)
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