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Sedentary work and breast cancer risk: A systematic review and meta‐analysis

Journal of occupational health, 2021-01, Vol.63 (1), p.n/a [Peer Reviewed Journal]

2021 The Authors. published by John Wiley & Sons Australia, Ltd on behalf of The Japan Society for Occupational Health ;2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1348-9585 ;ISSN: 1341-9145 ;EISSN: 1348-9585 ;DOI: 10.1002/1348-9585.12239 ;PMID: 34161650

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  • Title:
    Sedentary work and breast cancer risk: A systematic review and meta‐analysis
  • Author: Lee, Jongin ; Lee, JaeYong ; Lee, Dong‐Wook ; Kim, Hyoung‐Ryoul ; Kang, Mo‐Yeol
  • Subjects: Body mass ; Body mass index ; Body size ; Breast cancer ; breast neoplasms ; Health risks ; Hormone replacement therapy ; Menopause ; Meta-analysis ; Physical activity ; Review ; Risk ; sedentary behavior ; sedentary work ; Socioeconomic factors ; systematic review ; Womens health
  • Is Part Of: Journal of occupational health, 2021-01, Vol.63 (1), p.n/a
  • Description: Objectives This systematic review and meta‐analysis aimed to assess sedentary work's contribution to breast cancer risk quantitatively using thorough research articles. Methods We performed a meta‐analysis using a registered protocol in PROSPERO (registration number: CRD42020204629). Literature from PubMed, Embase, and Cochrane involving sedentary work and breast cancer risk was reviewed. We calculated the overall pooled risk ratios (RRs) and 95% CI with a random‐effect model from the included studies. Furthermore, we performed stratified analyses by characteristics of studies. Results Thirty‐one studies (13 cohort studies and 18 case‐control studies) were included in the analysis. The overall effect of the pooled analysis was an RR of 1.16 (95% CI 1.08‐1.23). The results were 1.20 (95% CI 1.10‐1.30) and 1.12 (95% CI 1.02‐1.23) for cohort and case‐control studies. The effect of sedentary work did not seem to be consistently attenuated by controlling body mass index, menopausal status, or experience of hormone replacement therapy. Conclusion The results from this meta‐analysis suggest that sedentary behavior within the occupational domain was associated with a 15.5% increased risk of breast cancer. It is essential to reduce the sedentary time spent at work and to secure time for leisure‐time physical activity among sedentary workers as a primary preventive measure.
  • Publisher: Tokyo: John Wiley & Sons, Inc
  • Language: English
  • Identifier: ISSN: 1348-9585
    ISSN: 1341-9145
    EISSN: 1348-9585
    DOI: 10.1002/1348-9585.12239
    PMID: 34161650
  • Source: Open Access: DOAJ Directory of Open Access Journals
    Open Access: PubMed Central
    Geneva Foundation Free Medical Journals at publisher websites
    ProQuest Central
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