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Naloxone induced pulmonary edema

Journal of Community Hospital Internal Medicine Perspectives, 2021, Vol.11 (1), p.139-142

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Title:
Naloxone induced pulmonary edema
Author: Elkattawy, Sherif ; Alyacoub, Ramez ; Ejikeme, Chidinma ; Noori, Muhammad Atif Masood ; Remolina, Carlos
Subjects: Naloxone ; opioids ; pulmonary edema
Is Part Of: Journal of Community Hospital Internal Medicine Perspectives, 2021, Vol.11 (1), p.139-142
Description: Naloxone-induced noncardiogenic pulmonary edema is a rare but reported entity that can occur following naloxone use in the reversal of opioid overdose. Proposed mechanisms include an adrenergic crisis secondary to catecholamine surge which causes more volume shift to pulmonary vasculature, subsequently leading to pulmonary edema. It appears to be more common when higher doses of naloxone are used. We present a case of a patient with opioid overdose came with altered mental status developed early features of pulmonary edema following the administration of multiple doses of naloxone. She responded well with the administration of diuretics and oxygen supplementation. Her oxygen requirements improved and didn't require mechanical ventilation.
Publisher: Taylor & Francis
Language: English
Identifier: EISSN: 2000-9666
DOI: 10.1080/20009666.2020.1854417
Source: Taylor & Francis Open Access
GFMER Free Medical Journals
PubMed Central
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