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Spontaneous Preterm Births in Malaysia: Are There Modifiable Antenatal Risk Factors?

Curēus (Palo Alto, CA), 2024-04, Vol.16 (4), p.e59152-e59152 [Peer Reviewed Journal]

Copyright © 2024, Damanhuri et al. ;Copyright © 2024, Damanhuri et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 2168-8184 ;EISSN: 2168-8184 ;DOI: 10.7759/cureus.59152 ;PMID: 38680821

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  • Title:
    Spontaneous Preterm Births in Malaysia: Are There Modifiable Antenatal Risk Factors?
  • Author: Damanhuri, Narisa H ; Hairi, Noran N ; Ismail, Maslinor ; Jeganathan, Ravichandran ; Karalasingam, Shamala D ; Nasir, Muhammad Jaffri Mohd ; Soelar, Shahrul Aiman ; Musa, Kamarul Imran ; Tengku Ismail, Tengku Alina
  • Subjects: Annual reports ; Birth rate ; Health facilities ; Mental disorders ; Mental health ; Multiple births ; Newborn babies ; Obstetrics ; Pregnancy ; Premature babies ; Premature birth ; Prenatal care ; Sociodemographics ; Socioeconomic factors ; Womens health
  • Is Part Of: Curēus (Palo Alto, CA), 2024-04, Vol.16 (4), p.e59152-e59152
  • Description: Background Spontaneous preterm birth (SPB) is a global public health concern with devastating health effects on SPB survivors. This study aimed to determine modifiable antenatal risk factors associated with SPB among women attending government healthcare facilities in Malaysia. Methodology A retrospective record review of 49,416 national obstetrics registry data from 2015 was conducted and analyzed using binary logistic regression based on six antenatal factor divisions. Results Mothers with pre-existing diabetes had higher odds (adjusted odds ratio (aOR) = 3.09) of delivering prematurely than mothers without diabetes. Mothers with chronic hypertension with superimposed pre-eclampsia (aOR = 2.51) and gestational hypertension (aOR = 1.44) had higher odds of experiencing preterm birth than mothers with no hypertension. Underweight mothers had higher odds (aOR = 1.27) of delivering prematurely than mothers with an ideal body mass index (18.5 to <25.0 kg/m ). Mothers with moderate anemia (hemoglobin level: 7 to <9 g/dL) had higher odds (aOR = 1.18) of preterm birth than mothers with normal hemoglobin levels (≥11 g/dL). Conclusions Maternal biomarkers, such as glucose level, blood pressure, BMI, and hemoglobin level, play an important role in reducing the rate of SPB in Malaysia. This study recommends strengthening pre-pregnancy, antenatal, and postpartum care through multidisciplinary and multi-agency team collaboration, addressing both modifiable and non-modifiable risk factors and adopting a dual approach that combines preventive and curative care.
  • Publisher: United States: Cureus Inc
  • Language: English
  • Identifier: ISSN: 2168-8184
    EISSN: 2168-8184
    DOI: 10.7759/cureus.59152
    PMID: 38680821
  • Source: PubMed Central
    ProQuest Central
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