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Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles

Nanoscale research letters, 2018-10, Vol.13 (1), p.339-12, Article 339 [Peer Reviewed Journal]

The Author(s). 2018 ;Nanoscale Research Letters is a copyright of Springer, (2018). All Rights Reserved. © 2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1931-7573 ;EISSN: 1556-276X ;DOI: 10.1186/s11671-018-2728-6 ;PMID: 30361809

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Title:
Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles
Author: Foroozandeh, Parisa ; Aziz, Azlan Abdul
Subjects: Cellular uptake ; Chemistry and Materials Science ; Cytotoxicity ; Intracellular ; Intracellular trafficking ; Long-term effects ; Materials Science ; Medical treatment ; Molecular Medicine ; Nano Review ; Nanochemistry ; Nanomedicine ; Nanoparticles ; Nanoscale Science and Technology ; Nanotechnology ; Nanotechnology and Microengineering ; Organic chemistry ; Physicochemical properties ; Surface charge ; Surface chemistry
Is Part Of: Nanoscale research letters, 2018-10, Vol.13 (1), p.339-12, Article 339
Description: Nanoparticle science is rapidly changing the landscape of various scientific fields and defining new technological platforms. This is perhaps even more evident in the field of nanomedicine whereby nanoparticles have been used as a tool for the treatment and diagnosis of many diseases. However, despite the tremendous benefit conferred, common pitfalls of this technology is its potential short and long-term effects on the human body. To understand these issues, many scientific studies have been carried out. This review attempts to shed light on some of these studies and its outcomes. The topics that were examined in this review include the different possible uptake pathways of nanoparticles and intracellular trafficking routes. Additionally, the effect of physicochemical properties of nanoparticle such as size, shape, charge and surface chemistry in determining the mechanism of uptake and biological function of nanoparticles are also addressed.
Publisher: New York: Springer US
Language: English
Identifier: ISSN: 1931-7573
EISSN: 1556-276X
DOI: 10.1186/s11671-018-2728-6
PMID: 30361809
Source: GFMER Free Medical Journals
PubMed Central
Alma/SFX Local Collection
Springer Nature OA/Free Journals
ProQuest Central
DOAJ Directory of Open Access Journals

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Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles

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