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Juvenile versus maturity-onset alopecia areata- a comparative retrospective clinical study

Clinical and experimental dermatology, 1989-11, Vol.14 (6), p.429-433 [Peer Reviewed Journal]

1990 INIST-CNRS ;ISSN: 0307-6938 ;EISSN: 1365-2230 ;DOI: 10.1111/j.1365-2230.1989.tb02604.x ;PMID: 2605805 ;CODEN: CEDEDE

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Title:
Juvenile versus maturity-onset alopecia areata- a comparative retrospective clinical study
Author: DE WAARD-VAN DER SPEK, F.B. ; ORANJE, A.P. ; DE RAEYMAECKER, D.M.J. ; PEEREBOOM-WYNIA, J.D.R.
Subjects: Adolescent ; Adult ; Age Factors ; Alopecia Areata - classification ; Alopecia Areata - immunology ; Alopecia Areata - psychology ; Autoantibodies - analysis ; Biological and medical sciences ; Chi-Square Distribution ; Child ; Child, Preschool ; Dermatology ; Female ; Hair and nails disorders ; Humans ; Hypersensitivity, Immediate - complications ; Male ; Medical sciences ; Nail Diseases - complications ; Prognosis ; Psychophysiologic Disorders ; Retrospective Studies
Is Part Of: Clinical and experimental dermatology, 1989-11, Vol.14 (6), p.429-433
Description: We report a retrospective study of 209 patients presenting with alopecia areata (AA) at our skin department during the period 1969-1987, with special reference to possible associations, aetiological factors and the relevance of additional investigations. The patients were divided into two groups: (I) those in whom AA developed during childhood; (II) those in whom AA developed in adult life (greater than or equal to 16 years). The aim of this study was to establish whether there is a difference between juvenile and maturity-onset AA and to consider the value of additional investigations in AA. Juvenile AA is more severe and has a less favourable prognosis than the maturity-onset disease. Statistically significant differences between the two groups were not found with respect to AA type and prevalence of auto-antibodies. Bad prognostic signs in AA were early age of onset, atopy (or first-degree family history) and ophiasis and/or onychodystrophy. Initial thyroid function testing seems advisable in patients with AA. Additional valuable investigations may include hair-root examination, determination of antibodies against thyroid tissue, and serum zinc levels. There are indications that psychosomatic factors may play a role in AA. In our study, psychosomatic factors were found in 29% of the juvenile AA and in 17% of the maturity-onset AA patients.
Publisher: Oxford, UK: Blackwell Publishing Ltd
Language: English
Identifier: ISSN: 0307-6938
EISSN: 1365-2230
DOI: 10.1111/j.1365-2230.1989.tb02604.x
PMID: 2605805
CODEN: CEDEDE
Source: MEDLINE
Alma/SFX Local Collection

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Juvenile versus maturity-onset alopecia areata- a comparative retrospective clinical study

1990 INIST-CNRS ;ISSN: 0307-6938 ;EISSN: 1365-2230 ;DOI: 10.1111/j.1365-2230.1989.tb02604.x ;PMID: 2605805 ;CODEN: CEDEDE

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